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The homeobox transcription factor HB9 induces senescence and blocks differentiation in hematopoietic stem and progenitor cells.
Ingenhag D, Reister S, Auer F, Bhatia S, Wildenhain S, Picard D, Remke M, Hoell JI, Kloetgen A, Sohn D, Jänicke RU, Koegler G, Borkhardt A, Hauer J. Ingenhag D, et al. Among authors: hauer j. Haematologica. 2019 Jan;104(1):35-46. doi: 10.3324/haematol.2018.189407. Epub 2018 Aug 9. Haematologica. 2019. PMID: 30093397 Free PMC article.
Anti-leukaemic activity of a novel haploidentical-transplantation approach employing unmanipulated bone marrow followed by CD6-depleted peripheral blood stem cells in children with refractory/relapsed acute leukaemia.
Schuster FR, Meisel R, Führer M, Reuther S, Hauer J, Tischer J, Feuchtinger T, Laws HJ, Kolb HJ, Borkhardt A. Schuster FR, et al. Among authors: hauer j. Br J Haematol. 2013 Sep;162(6):802-7. doi: 10.1111/bjh.12455. Epub 2013 Jul 6. Br J Haematol. 2013. PMID: 23829632 Free article.
Inherited susceptibility to pre B-ALL caused by germline transmission of PAX5 c.547G>A.
Auer F, Rüschendorf F, Gombert M, Husemann P, Ginzel S, Izraeli S, Harit M, Weintraub M, Weinstein OY, Lerer I, Stepensky P, Borkhardt A, Hauer J. Auer F, et al. Among authors: hauer j. Leukemia. 2014 May;28(5):1136-8. doi: 10.1038/leu.2013.363. Epub 2013 Nov 29. Leukemia. 2014. PMID: 24287434 No abstract available.
Infection Exposure is a Causal Factor in B-cell Precursor Acute Lymphoblastic Leukemia as a Result of Pax5-Inherited Susceptibility.
Martín-Lorenzo A, Hauer J, Vicente-Dueñas C, Auer F, González-Herrero I, García-Ramírez I, Ginzel S, Thiele R, Constantinescu SN, Bartenhagen C, Dugas M, Gombert M, Schäfer D, Blanco O, Mayado A, Orfao A, Alonso-López D, Rivas Jde L, Cobaleda C, García-Cenador MB, García-Criado FJ, Sánchez-García I, Borkhardt A. Martín-Lorenzo A, et al. Among authors: hauer j. Cancer Discov. 2015 Dec;5(12):1328-43. doi: 10.1158/2159-8290.CD-15-0892. Epub 2015 Sep 25. Cancer Discov. 2015. PMID: 26408659
GEMMs addressing Pax5 loss-of-function in childhood pB-ALL.
Auer F, Ingenhag D, Bhatia S, Enczmann J, Cobaleda C, Sanchez-Garcia I, Borkhardt A, Hauer J. Auer F, et al. Among authors: hauer j. Eur J Med Genet. 2016 Mar;59(3):166-72. doi: 10.1016/j.ejmg.2015.11.009. Epub 2015 Nov 26. Eur J Med Genet. 2016. PMID: 26626503 Review.
236 results