Villalta PW - Search Results

1

In Vivo Stable-Isotope Labeling and Mass-Spectrometry-Based Metabolic Profiling of a Potent Tobacco-Specific Carcinogen in Rats.

Dator R, von Weymarn LB, Villalta PW, Hooyman CJ, Maertens LA, Upadhyaya P, Murphy SE, Balbo S. Dator R, et al. Among authors: villalta pw. Anal Chem. 2018 Oct 16;90(20):11863-11872. doi: 10.1021/acs.analchem.8b01881. Epub 2018 Oct 4. Anal Chem. 2018. PMID: 30086646 Free PMC article.

2

2'-Hydroxylation of nicotine by cytochrome P450 2A6 and human liver microsomes: formation of a lung carcinogen precursor.

Hecht SS, Hochalter JB, Villalta PW, Murphy SE. Hecht SS, et al. Among authors: villalta pw. Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12493-7. doi: 10.1073/pnas.220207697. Proc Natl Acad Sci U S A. 2000. PMID: 11050152 Free PMC article.

3

Reactions of alpha-acetoxy-N-nitrosopyrrolidine with deoxyguanosine and DNA.

Wang M, McIntee EJ, Shi Y, Cheng G, Upadhyaya P, Villalta PW, Hecht SS. Wang M, et al. Among authors: villalta pw. Chem Res Toxicol. 2001 Oct;14(10):1435-45. doi: 10.1021/tx010097i. Chem Res Toxicol. 2001. PMID: 11599936

4

Identification of adducts produced by the reaction of 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanol with deoxyguanosine and DNA.

Upadhyaya P, Sturla SJ, Tretyakova N, Ziegel R, Villalta PW, Wang M, Hecht SS. Upadhyaya P, et al. Among authors: villalta pw. Chem Res Toxicol. 2003 Feb;16(2):180-90. doi: 10.1021/tx0256376. Chem Res Toxicol. 2003. PMID: 12588189

5

Identification of adducts formed by pyridyloxobutylation of deoxyguanosine and DNA by 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone, a chemically activated form of tobacco specific carcinogens.

Wang M, Cheng G, Sturla SJ, Shi Y, McIntee EJ, Villalta PW, Upadhyaya P, Hecht SS. Wang M, et al. Among authors: villalta pw. Chem Res Toxicol. 2003 May;16(5):616-26. doi: 10.1021/tx034003b. Chem Res Toxicol. 2003. PMID: 12755591

6

Identification of O2-substituted pyrimidine adducts formed in reactions of 4-(acetoxymethylnitrosamino)- 1-(3-pyridyl)-1-butanone and 4-(acetoxymethylnitros- amino)-1-(3-pyridyl)-1-butanol with DNA.

Hecht SS, Villalta PW, Sturla SJ, Cheng G, Yu N, Upadhyaya P, Wang M. Hecht SS, et al. Among authors: villalta pw. Chem Res Toxicol. 2004 May;17(5):588-97. doi: 10.1021/tx034263t. Chem Res Toxicol. 2004. PMID: 15144215

7

Mass spectrometric analysis of relative levels of pyridyloxobutylation adducts formed in the reaction of DNA with a chemically activated form of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

Sturla SJ, Scott J, Lao Y, Hecht SS, Villalta PW. Sturla SJ, et al. Among authors: villalta pw. Chem Res Toxicol. 2005 Jun;18(6):1048-55. doi: 10.1021/tx050028u. Chem Res Toxicol. 2005. PMID: 15962940

8

Analysis of total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in smokers' blood.

Carmella SG, Han S, Villalta PW, Hecht SS. Carmella SG, et al. Among authors: villalta pw. Cancer Epidemiol Biomarkers Prev. 2005 Nov;14(11 Pt 1):2669-72. doi: 10.1158/1055-9965.EPI-05-0129. Cancer Epidemiol Biomarkers Prev. 2005. PMID: 16284395

9

Identification of adducts formed in the reaction of 5'-acetoxy-N'-nitrosonornicotine with deoxyguanosine and DNA.

Upadhyaya P, McIntee EJ, Villalta PW, Hecht SS. Upadhyaya P, et al. Among authors: villalta pw. Chem Res Toxicol. 2006 Mar;19(3):426-35. doi: 10.1021/tx050323e. Chem Res Toxicol. 2006. PMID: 16544948 Free PMC article.

10

Quantitation of pyridyloxobutyl DNA adducts of tobacco-specific nitrosamines in rat tissue DNA by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry.

Lao Y, Villalta PW, Sturla SJ, Wang M, Hecht SS. Lao Y, et al. Among authors: villalta pw. Chem Res Toxicol. 2006 May;19(5):674-82. doi: 10.1021/tx050351x. Chem Res Toxicol. 2006. PMID: 16696570 Free PMC article.

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