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Page 1
Development of a gut microbe-targeted nonlethal therapeutic to inhibit thrombosis potential.
Roberts AB, Gu X, Buffa JA, Hurd AG, Wang Z, Zhu W, Gupta N, Skye SM, Cody DB, Levison BS, Barrington WT, Russell MW, Reed JM, Duzan A, Lang JM, Fu X, Li L, Myers AJ, Rachakonda S, DiDonato JA, Brown JM, Gogonea V, Lusis AJ, Garcia-Garcia JC, Hazen SL. Roberts AB, et al. Among authors: hurd ag. Nat Med. 2018 Sep;24(9):1407-1417. doi: 10.1038/s41591-018-0128-1. Epub 2018 Aug 6. Nat Med. 2018. PMID: 30082863 Free PMC article.
Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk.
Li XS, Wang Z, Cajka T, Buffa JA, Nemet I, Hurd AG, Gu X, Skye SM, Roberts AB, Wu Y, Li L, Shahen CJ, Wagner MA, Hartiala JA, Kerby RL, Romano KA, Han Y, Obeid S, Lüscher TF, Allayee H, Rey FE, DiDonato JA, Fiehn O, Tang WHW, Hazen SL. Li XS, et al. Among authors: hurd ag. JCI Insight. 2018 Mar 22;3(6):e99096. doi: 10.1172/jci.insight.99096. JCI Insight. 2018. PMID: 29563342 Free PMC article.
Trimethyllysine, a trimethylamine N-oxide precursor, provides near- and long-term prognostic value in patients presenting with acute coronary syndromes.
Li XS, Obeid S, Wang Z, Hazen BJ, Li L, Wu Y, Hurd AG, Gu X, Pratt A, Levison BS, Chung YM, Nissen SE, Tang WHW, Mach F, Räber L, Nanchen D, Matter CM, Lüscher TF, Hazen SL. Li XS, et al. Among authors: hurd ag. Eur Heart J. 2019 Aug 21;40(32):2700-2709. doi: 10.1093/eurheartj/ehz259. Eur Heart J. 2019. PMID: 31049589 Free PMC article.