Young JD - Search Results

1

Metabolic network-based predictions of toxicant-induced metabolite changes in the laboratory rat.

Pannala VR, Wall ML, Estes SK, Trenary I, O'Brien TP, Printz RL, Vinnakota KC, Reifman J, Shiota M, Young JD, Wallqvist A. Pannala VR, et al. Among authors: young jd. Sci Rep. 2018 Aug 3;8(1):11678. doi: 10.1038/s41598-018-30149-7. Sci Rep. 2018. PMID: 30076366 Free PMC article.

2

Palmitate-induced activation of mitochondrial metabolism promotes oxidative stress and apoptosis in H4IIEC3 rat hepatocytes.

Egnatchik RA, Leamy AK, Noguchi Y, Shiota M, Young JD. Egnatchik RA, et al. Among authors: young jd. Metabolism. 2014 Feb;63(2):283-95. doi: 10.1016/j.metabol.2013.10.009. Epub 2013 Oct 24. Metabolism. 2014. PMID: 24286856 Free PMC article.

3

Enhanced synthesis of saturated phospholipids is associated with ER stress and lipotoxicity in palmitate treated hepatic cells.

Leamy AK, Egnatchik RA, Shiota M, Ivanova PT, Myers DS, Brown HA, Young JD. Leamy AK, et al. Among authors: young jd. J Lipid Res. 2014 Jul;55(7):1478-88. doi: 10.1194/jlr.M050237. Epub 2014 May 23. J Lipid Res. 2014. PMID: 24859739 Free PMC article.

4

ER calcium release promotes mitochondrial dysfunction and hepatic cell lipotoxicity in response to palmitate overload.

Egnatchik RA, Leamy AK, Jacobson DA, Shiota M, Young JD. Egnatchik RA, et al. Among authors: young jd. Mol Metab. 2014 May 22;3(5):544-53. doi: 10.1016/j.molmet.2014.05.004. eCollection 2014 Aug. Mol Metab. 2014. PMID: 25061559 Free PMC article.

5

(13)C metabolic flux analysis of recombinant expression hosts.

Young JD. Young JD. Curr Opin Biotechnol. 2014 Dec;30:238-45. doi: 10.1016/j.copbio.2014.10.004. Epub 2014 Oct 29. Curr Opin Biotechnol. 2014. PMID: 25456032 Review.

6

Novel stable isotope analyses demonstrate significant rates of glucose cycling in mouse pancreatic islets.

Wall ML, Pound LD, Trenary I, O'Brien RM, Young JD. Wall ML, et al. Among authors: young jd. Diabetes. 2015 Jun;64(6):2129-37. doi: 10.2337/db14-0745. Epub 2014 Dec 31. Diabetes. 2015. PMID: 25552595 Free PMC article.

7

Mass spectrometry-based microassay of (2)H and (13)C plasma glucose labeling to quantify liver metabolic fluxes in vivo.

Hasenour CM, Wall ML, Ridley DE, Hughey CC, James FD, Wasserman DH, Young JD. Hasenour CM, et al. Among authors: young jd. Am J Physiol Endocrinol Metab. 2015 Jul 15;309(2):E191-203. doi: 10.1152/ajpendo.00003.2015. Epub 2015 May 19. Am J Physiol Endocrinol Metab. 2015. PMID: 25991647 Free PMC article.

8

LKB1 deficiency enhances sensitivity to energetic stress induced by erlotinib treatment in non-small-cell lung cancer (NSCLC) cells.

Whang YM, Park SI, Trenary IA, Egnatchik RA, Fessel JP, Kaufman JM, Carbone DP, Young JD. Whang YM, et al. Among authors: young jd. Oncogene. 2016 Feb 18;35(7):856-66. doi: 10.1038/onc.2015.140. Epub 2015 Jun 29. Oncogene. 2016. PMID: 26119936 Free PMC article.

9

Knockdown of triglyceride synthesis does not enhance palmitate lipotoxicity or prevent oleate-mediated rescue in rat hepatocytes.

Leamy AK, Hasenour CM, Egnatchik RA, Trenary IA, Yao CH, Patti GJ, Shiota M, Young JD. Leamy AK, et al. Among authors: young jd. Biochim Biophys Acta. 2016 Sep;1861(9 Pt A):1005-1014. doi: 10.1016/j.bbalip.2016.05.013. Epub 2016 May 29. Biochim Biophys Acta. 2016. PMID: 27249207 Free PMC article.

10

Oncogenic KRAS and BRAF Drive Metabolic Reprogramming in Colorectal Cancer.

Hutton JE, Wang X, Zimmerman LJ, Slebos RJ, Trenary IA, Young JD, Li M, Liebler DC. Hutton JE, et al. Among authors: young jd. Mol Cell Proteomics. 2016 Sep;15(9):2924-38. doi: 10.1074/mcp.M116.058925. Epub 2016 Jun 23. Mol Cell Proteomics. 2016. PMID: 27340238 Free PMC article.

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