Singh K - Search Results

1

Contribution of a Multifunctional Polymerase Region of Foot-and-Mouth Disease Virus to Lethal Mutagenesis.

de la Higuera I, Ferrer-Orta C, Moreno E, de Ávila AI, Soria ME, Singh K, Caridi F, Sobrino F, Sarafianos SG, Perales C, Verdaguer N, Domingo E. de la Higuera I, et al. Among authors: singh k. J Virol. 2018 Sep 26;92(20):e01119-18. doi: 10.1128/JVI.01119-18. Print 2018 Oct 15. J Virol. 2018. PMID: 30068642 Free PMC article.

2

Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.

Ferrer-Orta C, de la Higuera I, Caridi F, Sánchez-Aparicio MT, Moreno E, Perales C, Singh K, Sarafianos SG, Sobrino F, Domingo E, Verdaguer N. Ferrer-Orta C, et al. Among authors: singh k. J Virol. 2015 Jul;89(13):6848-59. doi: 10.1128/JVI.03283-14. Epub 2015 Apr 22. J Virol. 2015. PMID: 25903341 Free PMC article.

3

Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus.

de la Higuera I, Ferrer-Orta C, de Ávila AI, Perales C, Sierra M, Singh K, Sarafianos SG, Dehouck Y, Bastolla U, Verdaguer N, Domingo E. de la Higuera I, et al. Among authors: singh k. Genome Biol Evol. 2017 May 1;9(5):1212-1228. doi: 10.1093/gbe/evx075. Genome Biol Evol. 2017. PMID: 28460010 Free PMC article.

4

Repeated exposure to 5D9, an inhibitor of 3D polymerase, effectively limits the replication of foot-and-mouth disease virus in host cells.

Rai DK, Schafer EA, Singh K, McIntosh MA, Sarafianos SG, Rieder E. Rai DK, et al. Among authors: singh k. Antiviral Res. 2013 Jun;98(3):380-5. doi: 10.1016/j.antiviral.2013.03.022. Epub 2013 Apr 8. Antiviral Res. 2013. PMID: 23578728 Free PMC article.

5

Novel inhibitors of severe acute respiratory syndrome coronavirus entry that act by three distinct mechanisms.

Adedeji AO, Severson W, Jonsson C, Singh K, Weiss SR, Sarafianos SG. Adedeji AO, et al. Among authors: singh k. J Virol. 2013 Jul;87(14):8017-28. doi: 10.1128/JVI.00998-13. Epub 2013 May 15. J Virol. 2013. PMID: 23678171 Free PMC article.

6

Inhibitors of foot and mouth disease virus targeting a novel pocket of the RNA-dependent RNA polymerase.

Durk RC, Singh K, Cornelison CA, Rai DK, Matzek KB, Leslie MD, Schafer E, Marchand B, Adedeji A, Michailidis E, Dorst CA, Moran J, Pautler C, Rodriguez LL, McIntosh MA, Rieder E, Sarafianos SG. Durk RC, et al. Among authors: singh k. PLoS One. 2010 Dec 21;5(12):e15049. doi: 10.1371/journal.pone.0015049. PLoS One. 2010. PMID: 21203539 Free PMC article.

7

Increased replication capacity following evolution of PYxE insertion in Gag-p6 is associated with enhanced virulence in HIV-1 subtype C from East Africa.

Aralaguppe SG, Winner D, Singh K, Sarafianos SG, Quiñones-Mateu ME, Sönnerborg A, Neogi U. Aralaguppe SG, et al. Among authors: singh k. J Med Virol. 2017 Jan;89(1):106-111. doi: 10.1002/jmv.24610. Epub 2016 Jul 6. J Med Virol. 2017. PMID: 27328744

8

The N348I mutation at the connection subdomain of HIV-1 reverse transcriptase decreases binding to nevirapine.

Schuckmann MM, Marchand B, Hachiya A, Kodama EN, Kirby KA, Singh K, Sarafianos SG. Schuckmann MM, et al. Among authors: singh k. J Biol Chem. 2010 Dec 3;285(49):38700-9. doi: 10.1074/jbc.M110.153783. Epub 2010 Sep 27. J Biol Chem. 2010. PMID: 20876531 Free PMC article.

9

Mechanism of nucleic acid unwinding by SARS-CoV helicase.

Adedeji AO, Marchand B, Te Velthuis AJ, Snijder EJ, Weiss S, Eoff RL, Singh K, Sarafianos SG. Adedeji AO, et al. Among authors: singh k. PLoS One. 2012;7(5):e36521. doi: 10.1371/journal.pone.0036521. Epub 2012 May 15. PLoS One. 2012. PMID: 22615777 Free PMC article.

10

Severe acute respiratory syndrome coronavirus replication inhibitor that interferes with the nucleic acid unwinding of the viral helicase.

Adedeji AO, Singh K, Calcaterra NE, DeDiego ML, Enjuanes L, Weiss S, Sarafianos SG. Adedeji AO, et al. Among authors: singh k. Antimicrob Agents Chemother. 2012 Sep;56(9):4718-28. doi: 10.1128/AAC.00957-12. Epub 2012 Jun 25. Antimicrob Agents Chemother. 2012. PMID: 22733076 Free PMC article.

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