Gunn-Moore F - Search Results

1

Overexpression of endophilin A1 exacerbates synaptic alterations in a mouse model of Alzheimer's disease.

Yu Q, Wang Y, Du F, Yan S, Hu G, Origlia N, Rutigliano G, Sun Q, Yu H, Ainge J, Yan SF, Gunn-Moore F, Yan SS. Yu Q, et al. Nat Commun. 2018 Jul 30;9(1):2968. doi: 10.1038/s41467-018-04389-0. Nat Commun. 2018. PMID: 30061577 Free PMC article.

2

Mitochondrial β-amyloid in Alzheimer's disease.

Borger E, Aitken L, Muirhead KE, Allen ZE, Ainge JA, Conway SJ, Gunn-Moore FJ. Borger E, et al. Biochem Soc Trans. 2011 Aug;39(4):868-73. doi: 10.1042/BST0390868. Biochem Soc Trans. 2011. PMID: 21787315

3

Is amyloid binding alcohol dehydrogenase a drug target for treating Alzheimer's disease?

Borger E, Aitken L, Du H, Zhang W, Gunn-Moore FJ, Yan SS. Borger E, et al. Curr Alzheimer Res. 2013 Jan;10(1):21-9. Curr Alzheimer Res. 2013. PMID: 22742981 Free PMC article. Review.

4

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.

Lustbader JW, Cirilli M, Lin C, Xu HW, Takuma K, Wang N, Caspersen C, Chen X, Pollak S, Chaney M, Trinchese F, Liu S, Gunn-Moore F, Lue LF, Walker DG, Kuppusamy P, Zewier ZL, Arancio O, Stern D, Yan SS, Wu H. Lustbader JW, et al. Science. 2004 Apr 16;304(5669):448-52. doi: 10.1126/science.1091230. Science. 2004. PMID: 15087549

5

Inhibition of amyloid-beta (Abeta) peptide-binding alcohol dehydrogenase-Abeta interaction reduces Abeta accumulation and improves mitochondrial function in a mouse model of Alzheimer's disease.

Yao J, Du H, Yan S, Fang F, Wang C, Lue LF, Guo L, Chen D, Stern DM, Gunn Moore FJ, Xi Chen J, Arancio O, Yan SS. Yao J, et al. J Neurosci. 2011 Feb 9;31(6):2313-20. doi: 10.1523/JNEUROSCI.4717-10.2011. J Neurosci. 2011. PMID: 21307267 Free PMC article.

6

Endophilin I expression is increased in the brains of Alzheimer disease patients.

Ren Y, Xu HW, Davey F, Taylor M, Aiton J, Coote P, Fang F, Yao J, Chen D, Chen JX, Yan SD, Gunn-Moore FJ. Ren Y, et al. J Biol Chem. 2008 Feb 29;283(9):5685-91. doi: 10.1074/jbc.M707932200. Epub 2007 Dec 31. J Biol Chem. 2008. PMID: 18167351 Free article.

7

The Mitochondrial Enzyme 17βHSD10 Modulates Ischemic and Amyloid-β-Induced Stress in Primary Mouse Astrocytes.

Metodieva V, Smith T, Gunn-Moore F. Metodieva V, et al. Among authors: gunn moore f. eNeuro. 2022 Oct 6;9(5):ENEURO.0040-22.2022. doi: 10.1523/ENEURO.0040-22.2022. Print 2022 Sep-Oct. eNeuro. 2022. PMID: 36096650 Free PMC article.

8

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease.

Du H, Guo L, Fang F, Chen D, Sosunov AA, McKhann GM, Yan Y, Wang C, Zhang H, Molkentin JD, Gunn-Moore FJ, Vonsattel JP, Arancio O, Chen JX, Yan SD. Du H, et al. Nat Med. 2008 Oct;14(10):1097-105. doi: 10.1038/nm.1868. Epub 2008 Sep 21. Nat Med. 2008. PMID: 18806802 Free PMC article.

9

Willin/FRMD6 Mediates Mitochondrial Dysfunction Relevant to Neuronal Aβ Toxicity.

Chen D, Yu W, Aitken L, Gunn-Moore F. Chen D, et al. Among authors: gunn moore f. Cells. 2022 Oct 6;11(19):3140. doi: 10.3390/cells11193140. Cells. 2022. PMID: 36231104 Free PMC article.

10

Leptin prevents hippocampal synaptic disruption and neuronal cell death induced by amyloid β.

Doherty GH, Beccano-Kelly D, Yan SD, Gunn-Moore FJ, Harvey J. Doherty GH, et al. Neurobiol Aging. 2013 Jan;34(1):226-37. doi: 10.1016/j.neurobiolaging.2012.08.003. Epub 2012 Aug 22. Neurobiol Aging. 2013. PMID: 22921154

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