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EVI2B is a C/EBPα target gene required for granulocytic differentiation and functionality of hematopoietic progenitors.
Zjablovskaja P, Kardosova M, Danek P, Angelisova P, Benoukraf T, Wurm AA, Kalina T, Sian S, Balastik M, Delwel R, Brdicka T, Tenen DG, Behre G, Fiore F, Malissen B, Horejsi V, Alberich-Jorda M. Zjablovskaja P, et al. Cell Death Differ. 2017 Apr;24(4):705-716. doi: 10.1038/cdd.2017.6. Epub 2017 Feb 10. Cell Death Differ. 2017. PMID: 28186500 Free PMC article.
Disruption of the C/EBPα-miR-182 balance impairs granulocytic differentiation.
Wurm AA, Zjablovskaja P, Kardosova M, Gerloff D, Bräuer-Hartmann D, Katzerke C, Hartmann JU, Benoukraf T, Fricke S, Hilger N, Müller AM, Bill M, Schwind S, Tenen DG, Niederwieser D, Alberich-Jorda M, Behre G. Wurm AA, et al. Nat Commun. 2017 Jun 29;8(1):46. doi: 10.1038/s41467-017-00032-6. Nat Commun. 2017. PMID: 28663557 Free PMC article.
ZNF143 protein is an important regulator of the myeloid transcription factor C/EBPα.
Gonzalez D, Luyten A, Bartholdy B, Zhou Q, Kardosova M, Ebralidze A, Swanson KD, Radomska HS, Zhang P, Kobayashi SS, Welner RS, Levantini E, Steidl U, Chong G, Collombet S, Choi MH, Friedman AD, Scott LM, Alberich-Jorda M, Tenen DG. Gonzalez D, et al. J Biol Chem. 2017 Nov 17;292(46):18924-18936. doi: 10.1074/jbc.M117.811109. Epub 2017 Sep 12. J Biol Chem. 2017. PMID: 28900037 Free PMC article.
C/EBPγ is dispensable for steady-state and emergency granulopoiesis.
Kardosova M, Zjablovskaja P, Danek P, Angelisova P, de Figueiredo-Pontes LL, Welner RS, Brdicka T, Lee S, Tenen DG, Alberich-Jorda M. Kardosova M, et al. Haematologica. 2018 Aug;103(8):e331-e335. doi: 10.3324/haematol.2017.173781. Epub 2018 Mar 22. Haematologica. 2018. PMID: 29567783 Free PMC article. No abstract available.
Correction to: EVI2B is a C/EBPα target gene required for granulocytic differentiation and functionality of hematopoietic progenitors.
Zjablovskaja P, Kardosova M, Danek P, Angelisova P, Benoukraf T, Wurm AA, Kalina T, Sian S, Balastik M, Delwel R, Brdicka T, Tenen DG, Behre G, Fiore F, Malissen B, Horejsi V, Alberich-Jorda M. Zjablovskaja P, et al. Cell Death Differ. 2019 Jan;26(1):198. doi: 10.1038/s41418-018-0146-z. Cell Death Differ. 2019. PMID: 29991745 Free PMC article.
β-Catenin-TCF/LEF signaling promotes steady-state and emergency granulopoiesis via G-CSF receptor upregulation.
Danek P, Kardosova M, Janeckova L, Karkoulia E, Vanickova K, Fabisik M, Lozano-Asencio C, Benoukraf T, Tirado-Magallanes R, Zhou Q, Burocziova M, Rahmatova S, Pytlik R, Brdicka T, Tenen DG, Korinek V, Alberich-Jorda M. Danek P, et al. Blood. 2020 Nov 26;136(22):2574-2587. doi: 10.1182/blood.2019004664. Blood. 2020. PMID: 32822472 Free PMC article.
Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemia.
Zhang H, Alberich-Jorda M, Amabile G, Yang H, Staber PB, Di Ruscio A, Welner RS, Ebralidze A, Zhang J, Levantini E, Lefebvre V, Valk PJ, Delwel R, Hoogenkamp M, Nerlov C, Cammenga J, Saez B, Scadden DT, Bonifer C, Ye M, Tenen DG. Zhang H, et al. Cancer Cell. 2013 Nov 11;24(5):575-88. doi: 10.1016/j.ccr.2013.09.018. Epub 2013 Oct 31. Cancer Cell. 2013. PMID: 24183681 Free PMC article.
48 results