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Page 1
53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ.
Ghezraoui H, Oliveira C, Becker JR, Bilham K, Moralli D, Anzilotti C, Fischer R, Deobagkar-Lele M, Sanchiz-Calvo M, Fueyo-Marcos E, Bonham S, Kessler BM, Rottenberg S, Cornall RJ, Green CM, Chapman JR. Ghezraoui H, et al. Among authors: fueyo marcos e. Nature. 2018 Aug;560(7716):122-127. doi: 10.1038/s41586-018-0362-1. Epub 2018 Jul 25. Nature. 2018. PMID: 30046110 Free PMC article.
Activation of the integrated stress response is a vulnerability for multidrug-resistant FBXW7-deficient cells.
Sanchez-Burgos L, Navarro-González B, García-Martín S, Sirozh O, Mota-Pino J, Fueyo-Marcos E, Tejero H, Antón ME, Murga M, Al-Shahrour F, Fernandez-Capetillo O. Sanchez-Burgos L, et al. Among authors: fueyo marcos e. EMBO Mol Med. 2022 Sep 7;14(9):e15855. doi: 10.15252/emmm.202215855. Epub 2022 Jul 21. EMBO Mol Med. 2022. PMID: 35861150 Free PMC article.
SETD8 inhibition targets cancer cells with increased rates of ribosome biogenesis.
Murga M, Lopez-Pernas G, Soliva R, Fueyo-Marcos E, Amor C, Faustino I, Serna M, Serrano AG, Díaz L, Martínez S, Blanco-Aparicio C, Antón ME, Seashore-Ludlow B, Pastor J, Jafari R, Lafarga M, Llorca O, Orozco M, Fernández-Capetillo O. Murga M, et al. Among authors: fueyo marcos e. Cell Death Dis. 2024 Sep 28;15(9):694. doi: 10.1038/s41419-024-07106-6. Cell Death Dis. 2024. PMID: 39341827 Free PMC article.