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Page 1
A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer.
Saito T, Niida A, Uchi R, Hirata H, Komatsu H, Sakimura S, Hayashi S, Nambara S, Kuroda Y, Ito S, Eguchi H, Masuda T, Sugimachi K, Tobo T, Nishida H, Daa T, Chiba K, Shiraishi Y, Yoshizato T, Kodama M, Okimoto T, Mizukami K, Ogawa R, Okamoto K, Shuto M, Fukuda K, Matsui Y, Shimamura T, Hasegawa T, Doki Y, Nagayama S, Yamada K, Kato M, Shibata T, Mori M, Aburatani H, Murakami K, Suzuki Y, Ogawa S, Miyano S, Mimori K. Saito T, et al. Among authors: nagayama s. Nat Commun. 2018 Jul 23;9(1):2884. doi: 10.1038/s41467-018-05226-0. Nat Commun. 2018. PMID: 30038269 Free PMC article.
Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution.
Uchi R, Takahashi Y, Niida A, Shimamura T, Hirata H, Sugimachi K, Sawada G, Iwaya T, Kurashige J, Shinden Y, Iguchi T, Eguchi H, Chiba K, Shiraishi Y, Nagae G, Yoshida K, Nagata Y, Haeno H, Yamamoto H, Ishii H, Doki Y, Iinuma H, Sasaki S, Nagayama S, Yamada K, Yachida S, Kato M, Shibata T, Oki E, Saeki H, Shirabe K, Oda Y, Maehara Y, Komune S, Mori M, Suzuki Y, Yamamoto K, Aburatani H, Ogawa S, Miyano S, Mimori K. Uchi R, et al. Among authors: nagayama s. PLoS Genet. 2016 Feb 18;12(2):e1005778. doi: 10.1371/journal.pgen.1005778. eCollection 2016 Feb. PLoS Genet. 2016. PMID: 26890883 Free PMC article.
RAS mutation is a prognostic biomarker in colorectal cancer patients with metastasectomy.
Osumi H, Shinozaki E, Suenaga M, Matsusaka S, Konishi T, Akiyoshi T, Fujimoto Y, Nagayama S, Fukunaga Y, Ueno M, Mise Y, Ishizawa T, Inoue Y, Takahashi Y, Saiura A, Uehara H, Mun M, Okumura S, Mizunuma N, Miki Y, Yamaguchi T. Osumi H, et al. Among authors: nagayama s. Int J Cancer. 2016 Aug 15;139(4):803-11. doi: 10.1002/ijc.30106. Epub 2016 Apr 19. Int J Cancer. 2016. PMID: 27004837
Correction: Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution.
Uchi R, Takahashi Y, Niida A, Shimamura T, Hirata H, Sugimachi K, Sawada G, Iwaya T, Kurashige J, Shinden Y, Iguchi T, Eguchi H, Chiba K, Shiraishi Y, Nagae G, Yoshida K, Nagata Y, Haeno H, Yamamoto H, Ishii H, Doki Y, Iinuma H, Sasaki S, Nagayama S, Yamada K, Yachida S, Kato M, Shibata T, Oki E, Saeki H, Shirabe K, Oda Y, Maehara Y, Komune S, Mori M, Suzuki Y, Yamamoto K, Aburatani H, Ogawa S, Miyano S, Mimori K. Uchi R, et al. Among authors: nagayama s. PLoS Genet. 2017 May 19;13(5):e1006798. doi: 10.1371/journal.pgen.1006798. eCollection 2017 May. PLoS Genet. 2017. PMID: 28542232 Free PMC article.
GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12.
Tanikawa C, Kamatani Y, Takahashi A, Momozawa Y, Leveque K, Nagayama S, Mimori K, Mori M, Ishii H, Inazawa J, Yasuda J, Tsuboi A, Shimizu A, Sasaki M, Yamaji T, Sawada N, Iwasaki M, Tsugane S, Naito M, Wakai K, Koyama T, Takezaki T, Yuji K, Murakami Y, Nakamura Y, Kubo M, Matsuda K. Tanikawa C, et al. Among authors: nagayama s. Carcinogenesis. 2018 May 3;39(5):652-660. doi: 10.1093/carcin/bgy026. Carcinogenesis. 2018. PMID: 29471430
Comprehensive assay for the molecular profiling of cancer by target enrichment from formalin-fixed paraffin-embedded specimens.
Kohsaka S, Tatsuno K, Ueno T, Nagano M, Shinozaki-Ushiku A, Ushiku T, Takai D, Ikegami M, Kobayashi H, Kage H, Ando M, Hata K, Ueda H, Yamamoto S, Kojima S, Oseto K, Akaike K, Suehara Y, Hayashi T, Saito T, Takahashi F, Takahashi K, Takamochi K, Suzuki K, Nagayama S, Oda Y, Mimori K, Ishihara S, Yatomi Y, Nagase T, Nakajima J, Tanaka S, Fukayama M, Oda K, Nangaku M, Miyazono K, Miyagawa K, Aburatani H, Mano H. Kohsaka S, et al. Among authors: nagayama s. Cancer Sci. 2019 Apr;110(4):1464-1479. doi: 10.1111/cas.13968. Epub 2019 Mar 5. Cancer Sci. 2019. PMID: 30737998 Free PMC article.
Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis.
Kakiuchi N, Yoshida K, Uchino M, Kihara T, Akaki K, Inoue Y, Kawada K, Nagayama S, Yokoyama A, Yamamoto S, Matsuura M, Horimatsu T, Hirano T, Goto N, Takeuchi Y, Ochi Y, Shiozawa Y, Kogure Y, Watatani Y, Fujii Y, Kim SK, Kon A, Kataoka K, Yoshizato T, Nakagawa MM, Yoda A, Nanya Y, Makishima H, Shiraishi Y, Chiba K, Tanaka H, Sanada M, Sugihara E, Sato TA, Maruyama T, Miyoshi H, Taketo MM, Oishi J, Inagaki R, Ueda Y, Okamoto S, Okajima H, Sakai Y, Sakurai T, Haga H, Hirota S, Ikeuchi H, Nakase H, Marusawa H, Chiba T, Takeuchi O, Miyano S, Seno H, Ogawa S. Kakiuchi N, et al. Among authors: nagayama s. Nature. 2020 Jan;577(7789):260-265. doi: 10.1038/s41586-019-1856-1. Epub 2019 Dec 18. Nature. 2020. PMID: 31853061 Free article.
Impaired tumor immune response in metastatic tumors is a selective pressure for neutral evolution in CRC cases.
Sakimura S, Nagayama S, Fukunaga M, Hu Q, Kitagawa A, Kobayashi Y, Hasegawa T, Noda M, Kouyama Y, Shimizu D, Saito T, Niida A, Tsuruda Y, Otsu H, Matsumoto Y, Uchida H, Masuda T, Sugimachi K, Sasaki S, Yamada K, Takahashi K, Innan H, Suzuki Y, Nakamura H, Totoki Y, Mizuno S, Ohshima M, Shibata T, Mimori K. Sakimura S, et al. Among authors: nagayama s. PLoS Genet. 2021 Jan 21;17(1):e1009113. doi: 10.1371/journal.pgen.1009113. eCollection 2021 Jan. PLoS Genet. 2021. PMID: 33476333 Free PMC article.
409 results