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Antidepressants act by inducing autophagy controlled by sphingomyelin-ceramide.
Gulbins A, Schumacher F, Becker KA, Wilker B, Soddemann M, Boldrin F, Müller CP, Edwards MJ, Goodman M, Caldwell CC, Kleuser B, Kornhuber J, Szabo I, Gulbins E. Gulbins A, et al. Among authors: kornhuber j. Mol Psychiatry. 2018 Dec;23(12):2324-2346. doi: 10.1038/s41380-018-0090-9. Epub 2018 Jul 23. Mol Psychiatry. 2018. PMID: 30038230 Free PMC article.
The role of ceramide in major depressive disorder.
Kornhuber J, Reichel M, Tripal P, Groemer TW, Henkel AW, Mühle C, Gulbins E. Kornhuber J, et al. Eur Arch Psychiatry Clin Neurosci. 2009 Nov;259 Suppl 2:S199-204. doi: 10.1007/s00406-009-0061-x. Eur Arch Psychiatry Clin Neurosci. 2009. PMID: 19876679 Review.
Identification of novel functional inhibitors of acid sphingomyelinase.
Kornhuber J, Muehlbacher M, Trapp S, Pechmann S, Friedl A, Reichel M, Mühle C, Terfloth L, Groemer TW, Spitzer GM, Liedl KR, Gulbins E, Tripal P. Kornhuber J, et al. PLoS One. 2011;6(8):e23852. doi: 10.1371/journal.pone.0023852. Epub 2011 Aug 31. PLoS One. 2011. PMID: 21909365 Free PMC article.
Functional implications of novel human acid sphingomyelinase splice variants.
Rhein C, Tripal P, Seebahn A, Konrad A, Kramer M, Nagel C, Kemper J, Bode J, Mühle C, Gulbins E, Reichel M, Becker CM, Kornhuber J. Rhein C, et al. Among authors: kornhuber j. PLoS One. 2012;7(4):e35467. doi: 10.1371/journal.pone.0035467. Epub 2012 Apr 27. PLoS One. 2012. PMID: 22558155 Free PMC article.
1,014 results