Wilson DJ - Search Results

1

6-Arylthio-3-hydroxypyrimidine-2,4-diones potently inhibited HIV reverse transcriptase-associated RNase H with antiviral activity.

Wang L, Tang J, Huber AD, Casey MC, Kirby KA, Wilson DJ, Kankanala J, Xie J, Parniak MA, Sarafianos SG, Wang Z. Wang L, et al. Among authors: wilson dj. Eur J Med Chem. 2018 Aug 5;156:652-665. doi: 10.1016/j.ejmech.2018.07.039. Epub 2018 Jul 17. Eur J Med Chem. 2018. PMID: 30031976 Free PMC article.

2

Novel methylenephosphophosphonate analogues of mycophenolic adenine dinucleotide. Inhibition of inosine monophosphate dehydrogenase.

Rejman D, Olesiak M, Chen L, Patterson SE, Wilson D, Jayaram HN, Hedstrom L, Pankiewicz KW. Rejman D, et al. J Med Chem. 2006 Aug 10;49(16):5018-22. doi: 10.1021/jm060479r. J Med Chem. 2006. PMID: 16884314

3

Antitubercular nucleosides that inhibit siderophore biosynthesis: SAR of the glycosyl domain.

Somu RV, Wilson DJ, Bennett EM, Boshoff HI, Celia L, Beck BJ, Barry CE 3rd, Aldrich CC. Somu RV, et al. Among authors: wilson dj. J Med Chem. 2006 Dec 28;49(26):7623-35. doi: 10.1021/jm061068d. J Med Chem. 2006. PMID: 17181146 Free PMC article.

4

Rationally designed dual inhibitors of HIV reverse transcriptase and integrase.

Wang Z, Bennett EM, Wilson DJ, Salomon C, Vince R. Wang Z, et al. Among authors: wilson dj. J Med Chem. 2007 Jul 26;50(15):3416-9. doi: 10.1021/jm070512p. Epub 2007 Jul 4. J Med Chem. 2007. PMID: 17608468

5

Probing binding requirements of type I and type II isoforms of inosine monophosphate dehydrogenase with adenine-modified nicotinamide adenine dinucleotide analogues.

Chen L, Gao G, Felczak K, Bonnac L, Patterson SE, Wilson D, Bennett EM, Jayaram HN, Hedstrom L, Pankiewicz KW. Chen L, et al. J Med Chem. 2007 Nov 15;50(23):5743-51. doi: 10.1021/jm070568j. Epub 2007 Oct 24. J Med Chem. 2007. PMID: 17958343

6

5'-O-[(N-acyl)sulfamoyl]adenosines as antitubercular agents that inhibit MbtA: an adenylation enzyme required for siderophore biosynthesis of the mycobactins.

Qiao C, Gupte A, Boshoff HI, Wilson DJ, Bennett EM, Somu RV, Barry CE 3rd, Aldrich CC. Qiao C, et al. Among authors: wilson dj. J Med Chem. 2007 Nov 29;50(24):6080-94. doi: 10.1021/jm070905o. Epub 2007 Oct 30. J Med Chem. 2007. PMID: 17967002 Free PMC article.

7

Dual inhibitors of inosine monophosphate dehydrogenase and histone deacetylases for cancer treatment.

Chen L, Wilson D, Jayaram HN, Pankiewicz KW. Chen L, et al. J Med Chem. 2007 Dec 27;50(26):6685-91. doi: 10.1021/jm070864w. Epub 2007 Nov 27. J Med Chem. 2007. PMID: 18038969

8

Bis(sulfonamide) isosters of mycophenolic adenine dinucleotide analogues: inhibition of inosine monophosphate dehydrogenase.

Chen L, Petrelli R, Olesiak M, Wilson DJ, Labello NP, Pankiewicz KW. Chen L, et al. Among authors: wilson dj. Bioorg Med Chem. 2008 Aug 1;16(15):7462-9. doi: 10.1016/j.bmc.2008.06.003. Epub 2008 Jun 10. Bioorg Med Chem. 2008. PMID: 18583139

9

Inhibition of siderophore biosynthesis in Mycobacterium tuberculosis with nucleoside bisubstrate analogues: structure-activity relationships of the nucleobase domain of 5'-O-[N-(salicyl)sulfamoyl]adenosine.

Neres J, Labello NP, Somu RV, Boshoff HI, Wilson DJ, Vannada J, Chen L, Barry CE 3rd, Bennett EM, Aldrich CC. Neres J, et al. Among authors: wilson dj. J Med Chem. 2008 Sep 11;51(17):5349-70. doi: 10.1021/jm800567v. Epub 2008 Aug 9. J Med Chem. 2008. PMID: 18690677 Free PMC article.

10

Inhibition of siderophore biosynthesis by 2-triazole substituted analogues of 5'-O-[N-(salicyl)sulfamoyl]adenosine: antibacterial nucleosides effective against Mycobacterium tuberculosis.

Gupte A, Boshoff HI, Wilson DJ, Neres J, Labello NP, Somu RV, Xing C, Barry CE, Aldrich CC. Gupte A, et al. Among authors: wilson dj. J Med Chem. 2008 Dec 11;51(23):7495-507. doi: 10.1021/jm8008037. J Med Chem. 2008. PMID: 19053762 Free PMC article.

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