Wang L - Search Results

1

6-Arylthio-3-hydroxypyrimidine-2,4-diones potently inhibited HIV reverse transcriptase-associated RNase H with antiviral activity.

Wang L, Tang J, Huber AD, Casey MC, Kirby KA, Wilson DJ, Kankanala J, Xie J, Parniak MA, Sarafianos SG, Wang Z. Wang L, et al. Among authors: wang z. Eur J Med Chem. 2018 Aug 5;156:652-665. doi: 10.1016/j.ejmech.2018.07.039. Epub 2018 Jul 17. Eur J Med Chem. 2018. PMID: 30031976 Free PMC article.

2

6-Biphenylmethyl-3-hydroxypyrimidine-2,4-diones potently and selectively inhibited HIV reverse transcriptase-associated RNase H.

Wang L, Tang J, Huber AD, Casey MC, Kirby KA, Wilson DJ, Kankanala J, Parniak MA, Sarafianos SG, Wang Z. Wang L, et al. Among authors: wang z. Eur J Med Chem. 2018 Aug 5;156:680-691. doi: 10.1016/j.ejmech.2018.07.035. Epub 2018 Jul 17. Eur J Med Chem. 2018. PMID: 30031978 Free PMC article.

3

Cutting into the Substrate Dominance: Pharmacophore and Structure-Based Approaches toward Inhibiting Human Immunodeficiency Virus Reverse Transcriptase-Associated Ribonuclease H.

Wang L, Sarafianos SG, Wang Z. Wang L, et al. Among authors: wang z. Acc Chem Res. 2020 Jan 21;53(1):218-230. doi: 10.1021/acs.accounts.9b00450. Epub 2019 Dec 27. Acc Chem Res. 2020. PMID: 31880912 Free PMC article. Review.

4

Toward Structurally Novel and Metabolically Stable HIV-1 Capsid-Targeting Small Molecules.

Vernekar SKV, Sahani RL, Casey MC, Kankanala J, Wang L, Kirby KA, Du H, Zhang H, Tedbury PR, Xie J, Sarafianos SG, Wang Z. Vernekar SKV, et al. Among authors: wang l, wang z. Viruses. 2020 Apr 16;12(4):452. doi: 10.3390/v12040452. Viruses. 2020. PMID: 32316297 Free PMC article.

5

Targeting phosphatases: From molecule design to clinical trials.

Guo M, Li Z, Gu M, Gu J, You Q, Wang L. Guo M, et al. Among authors: wang l. Eur J Med Chem. 2024 Jan 15;264:116031. doi: 10.1016/j.ejmech.2023.116031. Epub 2023 Dec 8. Eur J Med Chem. 2024. PMID: 38101039 Review.

6

Small molecules targeting molecular chaperones for tau regulation: Achievements and challenges.

He C, Gu J, Wang D, Wang K, Wang Y, You Q, Wang L. He C, et al. Among authors: wang l, wang k, wang y, wang d. Eur J Med Chem. 2023 Dec 5;261:115859. doi: 10.1016/j.ejmech.2023.115859. Epub 2023 Oct 6. Eur J Med Chem. 2023. PMID: 37839344 Review.

7

Design and Synthesis of Cyclolipopeptide Mimics of Dysoxylactam A and Evaluation of the Reversing Potencies against P-Glycoprotein-Mediated Multidrug Resistance.

Yang GZ, Wang L, Gao K, Zhu X, Lou LG, Yue JM. Yang GZ, et al. Among authors: wang l. J Med Chem. 2024 Mar 28;67(6):4560-4582. doi: 10.1021/acs.jmedchem.3c01920. Epub 2024 Mar 19. J Med Chem. 2024. PMID: 38502936

8

Inhibition of the Ubiquitin Transfer Cascade by a Peptidomimetic Foldamer Mimicking the E2 N-Terminal Helix.

Zhou L, Jeong IH, Xue S, Xue M, Wang L, Li S, Liu R, Jeong GH, Wang X, Cai J, Yin J, Huang B. Zhou L, et al. Among authors: wang x, wang l. J Med Chem. 2023 Jan 12;66(1):491-502. doi: 10.1021/acs.jmedchem.2c01459. Epub 2022 Dec 26. J Med Chem. 2023. PMID: 36571278

9

Specific molecular recognition of mixed nucleic acid sequences: an aromatic dication that binds in the DNA minor groove as a dimer.

Wang L, Bailly C, Kumar A, Ding D, Bajic M, Boykin DW, Wilson WD. Wang L, et al. Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):12-6. doi: 10.1073/pnas.97.1.12. Proc Natl Acad Sci U S A. 2000. PMID: 10618362 Free PMC article.

10

Comparative thermodynamics for monomer and dimer sequence-dependent binding of a heterocyclic dication in the DNA minor groove.

Wang L, Kumar A, Boykin DW, Bailly C, Wilson WD. Wang L, et al. J Mol Biol. 2002 Mar 29;317(3):361-74. doi: 10.1006/jmbi.2002.5433. J Mol Biol. 2002. PMID: 11922670

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