Yap J - Search Results

1

The AMPK inhibitor overcomes the paradoxical effect of RAF inhibitors through blocking phospho-Ser-621 in the C terminus of CRAF.

Yuan J, Ng WH, Yap J, Chia B, Huang X, Wang M, Hu J. Yuan J, et al. Among authors: yap j. J Biol Chem. 2018 Sep 14;293(37):14276-14284. doi: 10.1074/jbc.RA118.004597. Epub 2018 Jul 20. J Biol Chem. 2018. PMID: 30030377 Free PMC article.

2

The dimer-dependent catalytic activity of RAF family kinases is revealed through characterizing their oncogenic mutants.

Yuan J, Ng WH, Lam PYP, Wang Y, Xia H, Yap J, Guan SP, Lee ASG, Wang M, Baccarini M, Hu J. Yuan J, et al. Among authors: yap j. Oncogene. 2018 Oct;37(43):5719-5734. doi: 10.1038/s41388-018-0365-2. Epub 2018 Jun 21. Oncogene. 2018. PMID: 29930381 Free PMC article.

3

Activating mutations in MEK1 enhance homodimerization and promote tumorigenesis.

Yuan J, Ng WH, Tian Z, Yap J, Baccarini M, Chen Z, Hu J. Yuan J, et al. Among authors: yap j. Sci Signal. 2018 Oct 30;11(554):eaar6795. doi: 10.1126/scisignal.aar6795. Sci Signal. 2018. PMID: 30377225

4

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods.

Yap J, Yuan J, Tee ZH, Huang X, Ng WH, Hu J. Yap J, et al. J Vis Exp. 2019 Jul 17;(149). doi: 10.3791/59795. J Vis Exp. 2019. PMID: 31380842

5

The MAPK and AMPK signalings: interplay and implication in targeted cancer therapy.

Yuan J, Dong X, Yap J, Hu J. Yuan J, et al. Among authors: yap j. J Hematol Oncol. 2020 Aug 17;13(1):113. doi: 10.1186/s13045-020-00949-4. J Hematol Oncol. 2020. PMID: 32807225 Free PMC article. Review.

6

The stability of R-spine defines RAF inhibitor resistance: A comprehensive analysis of oncogenic BRAF mutants with in-frame insertion of αC-β4 loop.

Yap J, Deepak RNVK, Tian Z, Ng WH, Goh KC, Foo A, Tee ZH, Mohanam MP, Sim YRM, Degirmenci U, Lam P, Chen Z, Fan H, Hu J. Yap J, et al. Sci Adv. 2021 Jun 9;7(24):eabg0390. doi: 10.1126/sciadv.abg0390. Print 2021 Jun. Sci Adv. 2021. PMID: 34108213 Free PMC article.

7

Drug resistance in targeted cancer therapies with RAF inhibitors.

Degirmenci U, Yap J, Sim YRM, Qin S, Hu J. Degirmenci U, et al. Among authors: yap j. Cancer Drug Resist. 2021 Jun 17;4(3):665-683. doi: 10.20517/cdr.2021.36. eCollection 2021. Cancer Drug Resist. 2021. PMID: 35582307 Free PMC article. Review.

8

The effect of ranitidine on the tuberculin skin test.

Yap JC, Wang YT. Yap JC, et al. Int J Tuberc Lung Dis. 1998 Apr;2(4):344-5. Int J Tuberc Lung Dis. 1998. PMID: 9559409 Clinical Trial. No abstract available.

9

A case of primary diffuse tracheobronchial amyloidosis treated by laser therapy.

Yap JC, Wang YT, Poh SC. Yap JC, et al. Singapore Med J. 1992 Apr;33(2):198-200. Singapore Med J. 1992. PMID: 1621131

10

The breathing patterns in Chinese and Indian adult males in the supine posture.

Yap JC, Wang YT, Poh SC. Yap JC, et al. Singapore Med J. 1990 Jun;31(3):225-7. Singapore Med J. 1990. PMID: 2392700

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