Brea J - Search Results

1

Clinical validation of blood/brain glutamate grabbing in acute ischemic stroke.

da Silva-Candal A, Pérez-Díaz A, Santamaría M, Correa-Paz C, Rodríguez-Yáñez M, Ardá A, Pérez-Mato M, Iglesias-Rey R, Brea J, Azuaje J, Sotelo E, Sobrino T, Loza MI, Castillo J, Campos F. da Silva-Candal A, et al. Among authors: brea j. Ann Neurol. 2018 Aug;84(2):260-273. doi: 10.1002/ana.25286. Epub 2018 Aug 22. Ann Neurol. 2018. PMID: 30014516 Clinical Trial.

2

Butyrophenone analogues in the carbazole series as potential atypical antipsychotics: synthesis and determination of affinities at D(2), 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.

Masaguer CF, Raviña E, Fontenla JA, Brea J, Tristán H, Loza MI. Masaguer CF, et al. Among authors: brea j. Eur J Med Chem. 2000 Jan;35(1):83-95. doi: 10.1016/s0223-5234(00)00109-4. Eur J Med Chem. 2000. PMID: 10733606

3

New serotonin 5-HT(2A), 5-HT(2B), and 5-HT(2C) receptor antagonists: synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo and heterocycloalkanones.

Brea J, Rodrigo J, Carrieri A, Sanz F, Cadavid MI, Enguix MJ, Villazón M, Mengod G, Caro Y, Masaguer CF, Raviña E, Centeno NB, Carotti A, Loza MI. Brea J, et al. J Med Chem. 2002 Jan 3;45(1):54-71. doi: 10.1021/jm011014y. J Med Chem. 2002. PMID: 11754579

4

Pyridazines. Part 28: 5-alkylidene-6-phenyl-3(2H)-pyridazinones, a new family of platelet aggregation inhibitors.

Sotelo E, Fraiz N, Yáñez M, Laguna R, Cano E, Brea J, Raviña E. Sotelo E, et al. Among authors: brea j. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1575-7. doi: 10.1016/s0960-894x(02)00246-9. Bioorg Med Chem Lett. 2002. PMID: 12039565

5

New arylpiperazine derivatives with high affinity for alpha1A, D2 and 5-HT2A receptors.

González-Gómez JC, Santana L, Uriarte E, Brea J, Villazón M, Loza MI, De Luca M, Rivas ME, Montenegro GY, Fontenla JA. González-Gómez JC, et al. Among authors: brea j. Bioorg Med Chem Lett. 2003 Jan 20;13(2):175-8. doi: 10.1016/s0960-894x(02)00933-2. Bioorg Med Chem Lett. 2003. PMID: 12482418

6

Conformationally constrained butyrophenones as new pharmacological tools to study 5-HT 2A and 5-HT 2C receptor behaviours.

Brea J, Masaguer CF, Villazón M, Cadavid MI, Raviña E, Fontaine F, Dezi C, Pastor M, Sanz F, Loza MI. Brea J, et al. Eur J Med Chem. 2003 Apr;38(4):433-40. doi: 10.1016/s0223-5234(03)00054-0. Eur J Med Chem. 2003. PMID: 12750032

7

Differential regulation of rat peripheral 5-HT(2A) and 5-HT(2B) receptor systems: influence of drug treatment.

Enguix MJ, Sánchez L, Villazón M, Brea J, Tristán H, Caruncho HJ, Cadavid MI, Loza MI. Enguix MJ, et al. Among authors: brea j. Naunyn Schmiedebergs Arch Pharmacol. 2003 Aug;368(2):79-90. doi: 10.1007/s00210-003-0775-7. Epub 2003 Jul 12. Naunyn Schmiedebergs Arch Pharmacol. 2003. PMID: 12861437

8

Different pharmacological properties of two equipotent antagonists (clozapine and rauwolscine) for 5-HT2B receptors in rat stomach fundus.

Villazón M, Enguix MJ, Tristán H, Honrubia MA, Brea J, Maayani S, Cadavid MI, Loza MI. Villazón M, et al. Among authors: brea j. Biochem Pharmacol. 2003 Sep 15;66(6):927-37. doi: 10.1016/s0006-2952(03)00426-x. Biochem Pharmacol. 2003. PMID: 12963479

9

Synthesis and biological activity of new potential agonists for the human adenosine A2A receptor.

Bosch MP, Campos F, Niubó I, Rosell G, Díaz JL, Brea J, Loza MI, Guerrero A. Bosch MP, et al. Among authors: brea j. J Med Chem. 2004 Jul 29;47(16):4041-53. doi: 10.1021/jm031143+. J Med Chem. 2004. PMID: 15267242

10

QF2004B, a potential antipsychotic butyrophenone derivative with similar pharmacological properties to clozapine.

Brea J, Castro M, Loza MI, Masaguer CF, Raviña E, Dezi C, Pastor M, Sanz F, Cabrero-Castel A, Galán-Rodríguez B, Fernández-Espejo E, Maldonado R, Robledo P. Brea J, et al. Neuropharmacology. 2006 Aug;51(2):251-62. doi: 10.1016/j.neuropharm.2006.03.021. Epub 2006 May 11. Neuropharmacology. 2006. PMID: 16697427

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