Zhou B - Search Results

1

Facile target validation in an animal model with intracellularly expressed monobodies.

Gupta A, Xu J, Lee S, Tsai ST, Zhou B, Kurosawa K, Werner MS, Koide A, Ruthenburg AJ, Dou Y, Koide S. Gupta A, et al. Among authors: zhou b. Nat Chem Biol. 2018 Sep;14(9):895-900. doi: 10.1038/s41589-018-0099-z. Epub 2018 Jul 16. Nat Chem Biol. 2018. PMID: 30013062 Free PMC article.

2

p53 Integrates Temporal WDR5 Inputs during Neuroectoderm and Mesoderm Differentiation of Mouse Embryonic Stem Cells.

Li Q, Mao F, Zhou B, Huang Y, Zou Z, denDekker AD, Xu J, Hou S, Liu J, Dou Y, Rao RC. Li Q, et al. Among authors: zhou b. Cell Rep. 2020 Jan 14;30(2):465-480.e6. doi: 10.1016/j.celrep.2019.12.039. Cell Rep. 2020. PMID: 31940490 Free PMC article.

3

p53 inactivation unmasks histone methylation-independent WDR5 functions that drive self-renewal and differentiation of pluripotent stem cells.

Li Q, Huang Y, Xu J, Mao F, Zhou B, Sun L, Basinski BW, Aksu M, Liu J, Dou Y, Rao RC. Li Q, et al. Among authors: zhou b. Stem Cell Reports. 2021 Nov 9;16(11):2642-2658. doi: 10.1016/j.stemcr.2021.10.002. Epub 2021 Oct 28. Stem Cell Reports. 2021. PMID: 34715053 Free PMC article.

4

ASH2L regulates ubiquitylation signaling to MLL: trans-regulation of H3 K4 methylation in higher eukaryotes.

Wu L, Lee SY, Zhou B, Nguyen UT, Muir TW, Tan S, Dou Y. Wu L, et al. Among authors: zhou b. Mol Cell. 2013 Mar 28;49(6):1108-20. doi: 10.1016/j.molcel.2013.01.033. Epub 2013 Feb 28. Mol Cell. 2013. PMID: 23453805 Free PMC article.

5

Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity.

Rogawski DS, Deng J, Li H, Miao H, Borkin D, Purohit T, Song J, Chase J, Li S, Ndoj J, Klossowski S, Kim E, Mao F, Zhou B, Ropa J, Krotoska MZ, Jin Z, Ernst P, Feng X, Huang G, Nishioka K, Kelly S, He M, Wen B, Sun D, Muntean A, Dou Y, Maillard I, Cierpicki T, Grembecka J. Rogawski DS, et al. Among authors: zhou b. Nat Commun. 2021 May 14;12(1):2792. doi: 10.1038/s41467-021-23152-6. Nat Commun. 2021. PMID: 33990599 Free PMC article.

6

H2B ubiquitylation promotes RNA Pol II processivity via PAF1 and pTEFb.

Wu L, Li L, Zhou B, Qin Z, Dou Y. Wu L, et al. Among authors: zhou b. Mol Cell. 2014 Jun 19;54(6):920-931. doi: 10.1016/j.molcel.2014.04.013. Epub 2014 May 15. Mol Cell. 2014. PMID: 24837678 Free PMC article.

7

PRDM16 Suppresses MLL1r Leukemia via Intrinsic Histone Methyltransferase Activity.

Zhou B, Wang J, Lee SY, Xiong J, Bhanu N, Guo Q, Ma P, Sun Y, Rao RC, Garcia BA, Hess JL, Dou Y. Zhou B, et al. Mol Cell. 2016 Apr 21;62(2):222-236. doi: 10.1016/j.molcel.2016.03.010. Epub 2016 Apr 14. Mol Cell. 2016. PMID: 27151440 Free PMC article.

8

Structural and functional analysis of the DOT1L-AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis.

Zhang H, Zhou B, Qin S, Xu J, Harding R, Tempel W, Nayak V, Li Y, Loppnau P, Dou Y, Min J. Zhang H, et al. Among authors: zhou b. Genes Dev. 2018 Mar 1;32(5-6):341-346. doi: 10.1101/gad.311639.118. Epub 2018 Mar 21. Genes Dev. 2018. PMID: 29563185 Free PMC article.

9

HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis.

Sun Y, Zhou B, Mao F, Xu J, Miao H, Zou Z, Phuc Khoa LT, Jang Y, Cai S, Witkin M, Koche R, Ge K, Dressler GR, Levine RL, Armstrong SA, Dou Y, Hess JL. Sun Y, et al. Among authors: zhou b. Cancer Cell. 2018 Oct 8;34(4):643-658.e5. doi: 10.1016/j.ccell.2018.08.018. Epub 2018 Sep 27. Cancer Cell. 2018. PMID: 30270123 Free PMC article.

10

MLL1 Inhibition Reprograms Epiblast Stem Cells to Naive Pluripotency.

Zhang H, Gayen S, Xiong J, Zhou B, Shanmugam AK, Sun Y, Karatas H, Liu L, Rao RC, Wang S, Nesvizhskii AI, Kalantry S, Dou Y. Zhang H, et al. Among authors: zhou b. Cell Stem Cell. 2016 Apr 7;18(4):481-94. doi: 10.1016/j.stem.2016.02.004. Epub 2016 Mar 17. Cell Stem Cell. 2016. PMID: 26996599 Free PMC article.

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