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Page 1
De Novo Design, Synthesis, and Biological Evaluation of 3,4-Disubstituted Pyrrolidine Sulfonamides as Potent and Selective Glycine Transporter 1 Competitive Inhibitors.
Wang Y, Zhao H, Brewer JT, Li H, Lao Y, Amberg W, Behl B, Akritopoulou-Zanze I, Dietrich J, Lange UEW, Pohlki F, Hoft C, Hornberger W, Djuric SW, Sydor J, Mezler M, Relo AL, Vasudevan A. Wang Y, et al. Among authors: relo al. J Med Chem. 2018 Sep 13;61(17):7486-7502. doi: 10.1021/acs.jmedchem.8b00295. Epub 2018 Jul 17. J Med Chem. 2018. PMID: 29969029
Discovery of Novel Aminotetralines and Aminochromanes as Selective and Competitive Glycine Transporter 1 (GlyT1) Inhibitors.
Amberg W, Lange UEW, Ochse M, Pohlki F, Behl B, Relo AL, Hornberger W, Hoft C, Mezler M, Sydor J, Wang Y, Zhao H, Brewer JT, Dietrich J, Li H, Akritopoulou-Zanze I, Lao Y, Hannick SM, Ku YY, Vasudevan A. Amberg W, et al. Among authors: relo al. J Med Chem. 2018 Sep 13;61(17):7503-7524. doi: 10.1021/acs.jmedchem.8b00300. Epub 2018 Aug 27. J Med Chem. 2018. PMID: 30080045
Towards trans-diagnostic mechanisms in psychiatry: neurobehavioral profile of rats with a loss-of-function point mutation in the dopamine transporter gene.
Vengeliene V, Bespalov A, Roßmanith M, Horschitz S, Berger S, Relo AL, Noori HR, Schneider P, Enkel T, Bartsch D, Schneider M, Behl B, Hansson AC, Schloss P, Spanagel R. Vengeliene V, et al. Among authors: relo al. Dis Model Mech. 2017 Apr 1;10(4):451-461. doi: 10.1242/dmm.027623. Epub 2017 Feb 6. Dis Model Mech. 2017. PMID: 28167616 Free PMC article.
Quantitative Systems Pharmacology Model for Alzheimer Disease Indicates Targeting Sphingolipid Dysregulation as Potential Treatment Option.
Clausznitzer D, Pichardo-Almarza C, Relo AL, van Bergeijk J, van der Kam E, Laplanche L, Benson N, Nijsen M. Clausznitzer D, et al. Among authors: relo al. CPT Pharmacometrics Syst Pharmacol. 2018 Nov;7(11):759-770. doi: 10.1002/psp4.12351. Epub 2018 Oct 8. CPT Pharmacometrics Syst Pharmacol. 2018. PMID: 30207429 Free PMC article.
Drug Tolerance: A Known Unknown in Translational Neuroscience.
Bespalov A, Müller R, Relo AL, Hudzik T. Bespalov A, et al. Among authors: relo al. Trends Pharmacol Sci. 2016 May;37(5):364-378. doi: 10.1016/j.tips.2016.01.008. Epub 2016 Feb 28. Trends Pharmacol Sci. 2016. PMID: 26935643 Review.