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Nucleobase Modified Adefovir (PMEA) Analogues as Potent and Selective Inhibitors of Adenylate Cyclases from Bordetella pertussis and Bacillus anthracis.
Česnek M, Skácel J, Jansa P, Dračínský M, Šmídková M, Mertlíková-Kaiserová H, Soto-Velasquez MP, Watts VJ, Janeba Z. Česnek M, et al. Among authors: jansa p. ChemMedChem. 2018 Sep 6;13(17):1779-1796. doi: 10.1002/cmdc.201800332. Epub 2018 Jul 31. ChemMedChem. 2018. PMID: 29968968 Free PMC article.
9-[2-(R)-(Phosphonomethoxy)propyl]-2,6-diaminopurine (R)-PMPDAP and its prodrugs: optimized preparation, including identification of by-products formed, and antiviral evaluation in vitro.
Krečmerová M, Jansa P, Dračínský M, Sázelová P, Kašička V, Neyts J, Auwerx J, Kiss E, Goris N, Stepan G, Janeba Z. Krečmerová M, et al. Among authors: jansa p. Bioorg Med Chem. 2013 Mar 1;21(5):1199-208. doi: 10.1016/j.bmc.2012.12.044. Epub 2013 Jan 9. Bioorg Med Chem. 2013. PMID: 23375089 Free PMC article.
The effect of novel [3-fluoro-(2-phosphonoethoxy)propyl]purines on the inhibition of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases.
Baszczyňski O, Hocková D, Janeba Z, Holý A, Jansa P, Dračínský M, Keough DT, Guddat LW. Baszczyňski O, et al. Among authors: jansa p. Eur J Med Chem. 2013 Sep;67:81-9. doi: 10.1016/j.ejmech.2013.06.032. Epub 2013 Jun 22. Eur J Med Chem. 2013. PMID: 23850568
Synthesis of novel purine-based coxsackievirus inhibitors bearing polycylic substituents at the N-9 position.
Dejmek M, Sála M, Plačková P, Hřebabecký H, Mascarell Borredà L, Neyts J, Dračínský M, Procházková E, Jansa P, Leyssen P, Mertlíková-Kaiserová H, Nencka R. Dejmek M, et al. Among authors: jansa p. Arch Pharm (Weinheim). 2014 Jul;347(7):478-85. doi: 10.1002/ardp.201300431. Epub 2014 Mar 20. Arch Pharm (Weinheim). 2014. PMID: 24652670
322 results