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Nucleobase Modified Adefovir (PMEA) Analogues as Potent and Selective Inhibitors of Adenylate Cyclases from Bordetella pertussis and Bacillus anthracis.
Česnek M, Skácel J, Jansa P, Dračínský M, Šmídková M, Mertlíková-Kaiserová H, Soto-Velasquez MP, Watts VJ, Janeba Z. Česnek M, et al. Among authors: janeba z. ChemMedChem. 2018 Sep 6;13(17):1779-1796. doi: 10.1002/cmdc.201800332. Epub 2018 Jul 31. ChemMedChem. 2018. PMID: 29968968 Free PMC article.
A novel and efficient one-pot synthesis of symmetrical diamide (bis-amidate) prodrugs of acyclic nucleoside phosphonates and evaluation of their biological activities.
Jansa P, Baszczyňski O, Dračínský M, Votruba I, Zídek Z, Bahador G, Stepan G, Cihlar T, Mackman R, Holý A, Janeba Z. Jansa P, et al. Among authors: janeba z. Eur J Med Chem. 2011 Sep;46(9):3748-54. doi: 10.1016/j.ejmech.2011.05.040. Epub 2011 May 23. Eur J Med Chem. 2011. PMID: 21664011
9-[2-(R)-(Phosphonomethoxy)propyl]-2,6-diaminopurine (R)-PMPDAP and its prodrugs: optimized preparation, including identification of by-products formed, and antiviral evaluation in vitro.
Krečmerová M, Jansa P, Dračínský M, Sázelová P, Kašička V, Neyts J, Auwerx J, Kiss E, Goris N, Stepan G, Janeba Z. Krečmerová M, et al. Among authors: janeba z. Bioorg Med Chem. 2013 Mar 1;21(5):1199-208. doi: 10.1016/j.bmc.2012.12.044. Epub 2013 Jan 9. Bioorg Med Chem. 2013. PMID: 23375089 Free PMC article.
The effect of novel [3-fluoro-(2-phosphonoethoxy)propyl]purines on the inhibition of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases.
Baszczyňski O, Hocková D, Janeba Z, Holý A, Jansa P, Dračínský M, Keough DT, Guddat LW. Baszczyňski O, et al. Among authors: janeba z. Eur J Med Chem. 2013 Sep;67:81-9. doi: 10.1016/j.ejmech.2013.06.032. Epub 2013 Jun 22. Eur J Med Chem. 2013. PMID: 23850568
81 results