Dahms SO - Search Results

1

Structural and functional analysis of cystatin E reveals enzymologically relevant dimer and amyloid fibril states.

Dall E, Hollerweger JC, Dahms SO, Cui H, Häussermann K, Brandstetter H. Dall E, et al. Among authors: dahms so. J Biol Chem. 2018 Aug 24;293(34):13151-13165. doi: 10.1074/jbc.RA118.002154. Epub 2018 Jul 2. J Biol Chem. 2018. PMID: 29967063 Free PMC article.

2

X-ray structures of human furin in complex with competitive inhibitors.

Dahms SO, Hardes K, Becker GL, Steinmetzer T, Brandstetter H, Than ME. Dahms SO, et al. ACS Chem Biol. 2014 May 16;9(5):1113-8. doi: 10.1021/cb500087x. Epub 2014 Apr 1. ACS Chem Biol. 2014. PMID: 24666235 Free PMC article.

3

The structure of a furin-antibody complex explains non-competitive inhibition by steric exclusion of substrate conformers.

Dahms SO, Creemers JW, Schaub Y, Bourenkov GP, Zögg T, Brandstetter H, Than ME. Dahms SO, et al. Sci Rep. 2016 Sep 27;6:34303. doi: 10.1038/srep34303. Sci Rep. 2016. PMID: 27670069 Free PMC article.

4

Sirtilins - the new old members of the vitamin K-dependent coagulation factor family.

Dahms SO, Demir F, Huesgen PF, Thorn K, Brandstetter H. Dahms SO, et al. J Thromb Haemost. 2019 Mar;17(3):470-481. doi: 10.1111/jth.14384. Epub 2019 Feb 13. J Thromb Haemost. 2019. PMID: 30644641 Free PMC article.

5

ExteNDing Proteome Coverage with Legumain as a Highly Specific Digestion Protease.

Soh WT, Demir F, Dall E, Perrar A, Dahms SO, Kuppusamy M, Brandstetter H, Huesgen PF. Soh WT, et al. Among authors: dahms so. Anal Chem. 2020 Feb 18;92(4):2961-2971. doi: 10.1021/acs.analchem.9b03604. Epub 2020 Jan 31. Anal Chem. 2020. PMID: 31951383 Free PMC article.

6

Structural and functional studies of Arabidopsis thaliana legumain beta reveal isoform specific mechanisms of activation and substrate recognition.

Dall E, Zauner FB, Soh WT, Demir F, Dahms SO, Cabrele C, Huesgen PF, Brandstetter H. Dall E, et al. Among authors: dahms so. J Biol Chem. 2020 Sep 11;295(37):13047-13064. doi: 10.1074/jbc.RA120.014478. Epub 2020 Jul 21. J Biol Chem. 2020. PMID: 32719006 Free PMC article.

7

The Basicity Makes the Difference: Improved Canavanine-Derived Inhibitors of the Proprotein Convertase Furin.

Lam van TV, Heindl MR, Schlutt C, Böttcher-Friebertshäuser E, Bartenschlager R, Klebe G, Brandstetter H, Dahms SO, Steinmetzer T. Lam van TV, et al. Among authors: dahms so. ACS Med Chem Lett. 2021 Feb 9;12(3):426-432. doi: 10.1021/acsmedchemlett.0c00651. eCollection 2021 Mar 11. ACS Med Chem Lett. 2021. PMID: 33732412 Free PMC article.

8

OFF-State-Specific Inhibition of the Proprotein Convertase Furin.

Dahms SO, Haider T, Klebe G, Steinmetzer T, Brandstetter H. Dahms SO, et al. ACS Chem Biol. 2021 Sep 17;16(9):1692-1700. doi: 10.1021/acschembio.1c00411. Epub 2021 Aug 20. ACS Chem Biol. 2021. PMID: 34415722 Free PMC article.

9

The Peptide Ligase Activity of Human Legumain Depends on Fold Stabilization and Balanced Substrate Affinities.

Dall E, Stanojlovic V, Demir F, Briza P, Dahms SO, Huesgen PF, Cabrele C, Brandstetter H. Dall E, et al. Among authors: dahms so. ACS Catal. 2021 Oct 1;11(19):11885-11896. doi: 10.1021/acscatal.1c02057. Epub 2021 Sep 10. ACS Catal. 2021. PMID: 34621593 Free PMC article.

10

Dichlorophenylpyridine-Based Molecules Inhibit Furin through an Induced-Fit Mechanism.

Dahms SO, Schnapp G, Winter M, Büttner FH, Schlepütz M, Gnamm C, Pautsch A, Brandstetter H. Dahms SO, et al. ACS Chem Biol. 2022 Apr 15;17(4):816-821. doi: 10.1021/acschembio.2c00103. Epub 2022 Apr 4. ACS Chem Biol. 2022. PMID: 35377598 Free PMC article.

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