Polaski JT - Search Results

1

A functional genetic screen reveals sequence preferences within a key tertiary interaction in cobalamin riboswitches required for ligand selectivity.

Polaski JT, Kletzien OA, Drogalis LK, Batey RT. Polaski JT, et al. Nucleic Acids Res. 2018 Sep 28;46(17):9094-9105. doi: 10.1093/nar/gky539. Nucleic Acids Res. 2018. PMID: 29945209 Free PMC article.

2

B12 cofactors directly stabilize an mRNA regulatory switch.

Johnson JE Jr, Reyes FE, Polaski JT, Batey RT. Johnson JE Jr, et al. Among authors: polaski jt. Nature. 2012 Dec 6;492(7427):133-7. doi: 10.1038/nature11607. Epub 2012 Oct 14. Nature. 2012. PMID: 23064232 Free PMC article.

3

Single-molecule conformational dynamics of a biologically functional hydroxocobalamin riboswitch.

Holmstrom ED, Polaski JT, Batey RT, Nesbitt DJ. Holmstrom ED, et al. Among authors: polaski jt. J Am Chem Soc. 2014 Dec 3;136(48):16832-43. doi: 10.1021/ja5076184. Epub 2014 Nov 19. J Am Chem Soc. 2014. PMID: 25325398 Free PMC article.

4

A Highly Coupled Network of Tertiary Interactions in the SAM-I Riboswitch and Their Role in Regulatory Tuning.

Wostenberg C, Ceres P, Polaski JT, Batey RT. Wostenberg C, et al. Among authors: polaski jt. J Mol Biol. 2015 Nov 6;427(22):3473-3490. doi: 10.1016/j.jmb.2015.07.027. Epub 2015 Sep 3. J Mol Biol. 2015. PMID: 26343759 Free PMC article.

5

Mechanistic Insights into Cofactor-Dependent Coupling of RNA Folding and mRNA Transcription/Translation by a Cobalamin Riboswitch.

Polaski JT, Holmstrom ED, Nesbitt DJ, Batey RT. Polaski JT, et al. Cell Rep. 2016 May 3;15(5):1100-1110. doi: 10.1016/j.celrep.2016.03.087. Epub 2016 Apr 21. Cell Rep. 2016. PMID: 27117410 Free PMC article.

6

Cobalamin riboswitches exhibit a broad range of ability to discriminate between methylcobalamin and adenosylcobalamin.

Polaski JT, Webster SM, Johnson JE Jr, Batey RT. Polaski JT, et al. J Biol Chem. 2017 Jul 14;292(28):11650-11658. doi: 10.1074/jbc.M117.787176. Epub 2017 May 8. J Biol Chem. 2017. PMID: 28483920 Free PMC article.

7

Recurrent RNA motifs as scaffolds for genetically encodable small-molecule biosensors.

Porter EB, Polaski JT, Morck MM, Batey RT. Porter EB, et al. Among authors: polaski jt. Nat Chem Biol. 2017 Mar;13(3):295-301. doi: 10.1038/nchembio.2278. Epub 2017 Jan 16. Nat Chem Biol. 2017. PMID: 28092358 Free PMC article.

8

A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells.

Braselmann E, Wierzba AJ, Polaski JT, Chromiński M, Holmes ZE, Hung ST, Batan D, Wheeler JR, Parker R, Jimenez R, Gryko D, Batey RT, Palmer AE. Braselmann E, et al. Among authors: polaski jt. Nat Chem Biol. 2018 Oct;14(10):964-971. doi: 10.1038/s41589-018-0103-7. Epub 2018 Jul 30. Nat Chem Biol. 2018. PMID: 30061719 Free PMC article.

9

RNA isoform screens uncover the essentiality and tumor-suppressor activity of ultraconserved poison exons.

Thomas JD, Polaski JT, Feng Q, De Neef EJ, Hoppe ER, McSharry MV, Pangallo J, Gabel AM, Belleville AE, Watson J, Nkinsi NT, Berger AH, Bradley RK. Thomas JD, et al. Among authors: polaski jt. Nat Genet. 2020 Jan;52(1):84-94. doi: 10.1038/s41588-019-0555-z. Epub 2020 Jan 7. Nat Genet. 2020. PMID: 31911676 Free PMC article.

10

Synthetic introns enable splicing factor mutation-dependent targeting of cancer cells.

North K, Benbarche S, Liu B, Pangallo J, Chen S, Stahl M, Bewersdorf JP, Stanley RF, Erickson C, Cho H, Pineda JMB, Thomas JD, Polaski JT, Belleville AE, Gabel AM, Udy DB, Humbert O, Kiem HP, Abdel-Wahab O, Bradley RK. North K, et al. Among authors: polaski jt. Nat Biotechnol. 2022 Jul;40(7):1103-1113. doi: 10.1038/s41587-022-01224-2. Epub 2022 Mar 3. Nat Biotechnol. 2022. PMID: 35241838 Free PMC article.

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