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Page 1
Antibody-mediated inhibition of FXIIa blocks downstream bradykinin generation.
Cao H, Biondo M, Lioe H, Busfield S, Rayzman V, Nieswandt B, Bork K, Harrison LC, Auyeung P, Farkas H, Csuka D, Pelzing M, Dower S, Wilson MJ, Nash A, Nolte MW, Panousis C. Cao H, et al. Among authors: nolte mw. J Allergy Clin Immunol. 2018 Oct;142(4):1355-1358. doi: 10.1016/j.jaci.2018.06.014. Epub 2018 Jun 21. J Allergy Clin Immunol. 2018. PMID: 29936101 No abstract available.
Pharmacological Inhibition of Factor XIIa Attenuates Abdominal Aortic Aneurysm, Reduces Atherosclerosis, and Stabilizes Atherosclerotic Plaques.
Searle AK, Chen YC, Wallert M, McFadyen JD, Maluenda AC, Noonan J, Kanellakis P, Zaldivia MTK, Huang A, Lioe H, Biondo M, Nolte MW, Rossato P, Bobik A, Panousis C, Wang X, Hosseini H, Peter K. Searle AK, et al. Among authors: nolte mw. Thromb Haemost. 2022 Feb;122(2):196-207. doi: 10.1055/a-1663-8208. Epub 2022 Jan 21. Thromb Haemost. 2022. PMID: 34619795 Free PMC article.
Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells.
Göbel K, Pankratz S, Asaridou CM, Herrmann AM, Bittner S, Merker M, Ruck T, Glumm S, Langhauser F, Kraft P, Krug TF, Breuer J, Herold M, Gross CC, Beckmann D, Korb-Pap A, Schuhmann MK, Kuerten S, Mitroulis I, Ruppert C, Nolte MW, Panousis C, Klotz L, Kehrel B, Korn T, Langer HF, Pap T, Nieswandt B, Wiendl H, Chavakis T, Kleinschnitz C, Meuth SG. Göbel K, et al. Among authors: nolte mw. Nat Commun. 2016 May 18;7:11626. doi: 10.1038/ncomms11626. Nat Commun. 2016. PMID: 27188843 Free PMC article.
Antihistone Properties of C1 Esterase Inhibitor Protect against Lung Injury.
Wygrecka M, Kosanovic D, Wujak L, Reppe K, Henneke I, Frey H, Didiasova M, Kwapiszewska G, Marsh LM, Baal N, Hackstein H, Zakrzewicz D, Müller-Redetzky HC, de Maat S, Maas C, Nolte MW, Panousis C, Schermuly RT, Seeger W, Witzenrath M, Schaefer L, Markart P. Wygrecka M, et al. Among authors: nolte mw. Am J Respir Crit Care Med. 2017 Jul 15;196(2):186-199. doi: 10.1164/rccm.201604-0712OC. Am J Respir Crit Care Med. 2017. PMID: 28005404
Targeting coagulation factor XII as a novel therapeutic option in brain trauma.
Hopp S, Albert-Weissenberger C, Mencl S, Bieber M, Schuhmann MK, Stetter C, Nieswandt B, Schmidt PM, Monoranu CM, Alafuzoff I, Marklund N, Nolte MW, Sirén AL, Kleinschnitz C. Hopp S, et al. Among authors: nolte mw. Ann Neurol. 2016 Jun;79(6):970-82. doi: 10.1002/ana.24655. Epub 2016 Apr 28. Ann Neurol. 2016. PMID: 27043916 Free PMC article.
A factor XIIa inhibitory antibody provides thromboprotection in extracorporeal circulation without increasing bleeding risk.
Larsson M, Rayzman V, Nolte MW, Nickel KF, Björkqvist J, Jämsä A, Hardy MP, Fries M, Schmidbauer S, Hedenqvist P, Broomé M, Pragst I, Dickneite G, Wilson MJ, Nash AD, Panousis C, Renné T. Larsson M, et al. Among authors: nolte mw. Sci Transl Med. 2014 Feb 5;6(222):222ra17. doi: 10.1126/scitranslmed.3006804. Sci Transl Med. 2014. PMID: 24500405
43 results