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The first knock-in rat model for glutaric aciduria type I allows further insights into pathophysiology in brain and periphery.
Gonzalez Melo M, Remacle N, Cudré-Cung HP, Roux C, Poms M, Cudalbu C, Barroso M, Gersting SW, Feichtinger RG, Mayr JA, Costanzo M, Caterino M, Ruoppolo M, Rüfenacht V, Häberle J, Braissant O, Ballhausen D. Gonzalez Melo M, et al. Mol Genet Metab. 2021 Jun;133(2):157-181. doi: 10.1016/j.ymgme.2021.03.017. Epub 2021 Apr 18. Mol Genet Metab. 2021. PMID: 33965309 Free article.
A knock-in rat model unravels acute and chronic renal toxicity in glutaric aciduria type I.
Gonzalez Melo M, Fontana AO, Viertl D, Allenbach G, Prior JO, Rotman S, Feichtinger RG, Mayr JA, Costanzo M, Caterino M, Ruoppolo M, Braissant O, Barbey F, Ballhausen D. Gonzalez Melo M, et al. Mol Genet Metab. 2021 Dec;134(4):287-300. doi: 10.1016/j.ymgme.2021.10.003. Epub 2021 Nov 10. Mol Genet Metab. 2021. PMID: 34799272 Free article.
PNPLA3 inhibition: Replacing one Evil with the Other?
von Eckardstein A, Gonzalez Melo MJ. von Eckardstein A, et al. Among authors: gonzalez melo mj. J Clin Endocrinol Metab. 2024 May 31:dgae377. doi: 10.1210/clinem/dgae377. Online ahead of print. J Clin Endocrinol Metab. 2024. PMID: 38820113 No abstract available.
Dual topologies of myotomal collagen XV and Tenascin C act in concert to guide and shape developing motor axons.
Nemoz-Billet L, Balland M, Gilquin L, Gillet B, Stévant I, Guillon E, Hughes S, Carpentier G, Vaganay E, Sohm F, Misiak V, Gonzalez-Melo MJ, Koch M, Ghavi-Helm Y, Bretaud S, Ruggiero F. Nemoz-Billet L, et al. Among authors: gonzalez melo mj. Proc Natl Acad Sci U S A. 2024 Mar 26;121(13):e2314588121. doi: 10.1073/pnas.2314588121. Epub 2024 Mar 19. Proc Natl Acad Sci U S A. 2024. PMID: 38502691 Free PMC article.