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Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles.
Merle NS, Grunenwald A, Rajaratnam H, Gnemmi V, Frimat M, Figueres ML, Knockaert S, Bouzekri S, Charue D, Noe R, Robe-Rybkine T, Le-Hoang M, Brinkman N, Gentinetta T, Edler M, Petrillo S, Tolosano E, Miescher S, Le Jeune S, Houillier P, Chauvet S, Rabant M, Dimitrov JD, Fremeaux-Bacchi V, Blanc-Brude OP, Roumenina LT. Merle NS, et al. Among authors: frimat m. JCI Insight. 2018 Jun 21;3(12):e96910. doi: 10.1172/jci.insight.96910. eCollection 2018 Jun 21. JCI Insight. 2018. PMID: 29925688 Free PMC article.
Sepsis-like Energy Deficit Is Not Sufficient to Induce Early Muscle Fiber Atrophy and Mitochondrial Dysfunction in a Murine Sepsis Model.
Pierre A, Bourel C, Favory R, Brassart B, Wallet F, Daussin FN, Normandin S, Howsam M, Romien R, Lemaire J, Grolaux G, Durand A, Frimat M, Bastide B, Amouyel P, Boulanger E, Preau S, Lancel S. Pierre A, et al. Among authors: frimat m. Biology (Basel). 2023 Mar 30;12(4):529. doi: 10.3390/biology12040529. Biology (Basel). 2023. PMID: 37106730 Free PMC article.
A prevalent C3 mutation in aHUS patients causes a direct C3 convertase gain of function.
Roumenina LT, Frimat M, Miller EC, Provot F, Dragon-Durey MA, Bordereau P, Bigot S, Hue C, Satchell SC, Mathieson PW, Mousson C, Noel C, Sautes-Fridman C, Halbwachs-Mecarelli L, Atkinson JP, Lionet A, Fremeaux-Bacchi V. Roumenina LT, et al. Among authors: frimat m. Blood. 2012 May 3;119(18):4182-91. doi: 10.1182/blood-2011-10-383281. Epub 2012 Jan 13. Blood. 2012. PMID: 22246034 Free PMC article.
Anti-Factor B and Anti-C3b Autoantibodies in C3 Glomerulopathy and Ig-Associated Membranoproliferative GN.
Marinozzi MC, Roumenina LT, Chauvet S, Hertig A, Bertrand D, Olagne J, Frimat M, Ulinski T, Deschênes G, Burtey S, Delahousse M, Moulin B, Legendre C, Frémeaux-Bacchi V, Le Quintrec M. Marinozzi MC, et al. Among authors: frimat m. J Am Soc Nephrol. 2017 May;28(5):1603-1613. doi: 10.1681/ASN.2016030343. Epub 2017 Jan 17. J Am Soc Nephrol. 2017. PMID: 28096309 Free PMC article.
59 results