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Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function.
Burkard C, Lillico SG, Reid E, Jackson B, Mileham AJ, Ait-Ali T, Whitelaw CB, Archibald AL. Burkard C, et al. Among authors: archibald al. PLoS Pathog. 2017 Feb 23;13(2):e1006206. doi: 10.1371/journal.ppat.1006206. eCollection 2017 Feb. PLoS Pathog. 2017. PMID: 28231264 Free PMC article.
Erratum for Burkard et al., "Pigs Lacking the Scavenger Receptor Cysteine-Rich Domain 5 of CD163 Are Resistant to Porcine Reproductive and Respiratory Syndrome Virus 1 Infection".
Burkard C, Opriessnig T, Mileham AJ, Stadejek T, Ait-Ali T, Lillico SG, Whitelaw CBA, Archibald AL. Burkard C, et al. Among authors: archibald al. J Virol. 2020 Jul 16;94(15):e00951-20. doi: 10.1128/JVI.00951-20. Print 2020 Jul 16. J Virol. 2020. PMID: 32675378 Free PMC article. No abstract available.
196 results