Moore EC - Search Results

1

Inhibition of WEE1 kinase and cell cycle checkpoint activation sensitizes head and neck cancers to natural killer cell therapies.

Friedman J, Morisada M, Sun L, Moore EC, Padget M, Hodge JW, Schlom J, Gameiro SR, Allen CT. Friedman J, et al. Among authors: moore ec. J Immunother Cancer. 2018 Jun 21;6(1):59. doi: 10.1186/s40425-018-0374-2. J Immunother Cancer. 2018. PMID: 29925431 Free PMC article.

2

Enhanced Tumor Control with Combination mTOR and PD-L1 Inhibition in Syngeneic Oral Cavity Cancers.

Moore EC, Cash HA, Caruso AM, Uppaluri R, Hodge JW, Van Waes C, Allen CT. Moore EC, et al. Cancer Immunol Res. 2016 Jul;4(7):611-20. doi: 10.1158/2326-6066.CIR-15-0252. Epub 2016 Apr 13. Cancer Immunol Res. 2016. PMID: 27076449 Free PMC article.

3

Anti-PD-L1 Efficacy Can Be Enhanced by Inhibition of Myeloid-Derived Suppressor Cells with a Selective Inhibitor of PI3Kδ/γ.

Davis RJ, Moore EC, Clavijo PE, Friedman J, Cash H, Chen Z, Silvin C, Van Waes C, Allen C. Davis RJ, et al. Among authors: moore ec. Cancer Res. 2017 May 15;77(10):2607-2619. doi: 10.1158/0008-5472.CAN-16-2534. Epub 2017 Mar 31. Cancer Res. 2017. PMID: 28364000 Free PMC article.

4

Semaphorin4D Inhibition Improves Response to Immune-Checkpoint Blockade via Attenuation of MDSC Recruitment and Function.

Clavijo PE, Friedman J, Robbins Y, Moore EC, Smith E, Zauderer M, Evans EE, Allen CT. Clavijo PE, et al. Among authors: moore ec. Cancer Immunol Res. 2019 Feb;7(2):282-291. doi: 10.1158/2326-6066.CIR-18-0156. Epub 2018 Dec 4. Cancer Immunol Res. 2019. PMID: 30514791 Free PMC article.

5

Neoadjuvant PD-1 Immune Checkpoint Blockade Reverses Functional Immunodominance among Tumor Antigen-Specific T Cells.

Friedman J, Moore EC, Zolkind P, Robbins Y, Clavijo PE, Sun L, Greene S, Morisada MV, Mydlarz WK, Schmitt N, Hodge JW, Schreiber H, Van Waes C, Uppaluri R, Allen C. Friedman J, et al. Among authors: moore ec. Clin Cancer Res. 2020 Feb 1;26(3):679-689. doi: 10.1158/1078-0432.CCR-19-2209. Epub 2019 Oct 23. Clin Cancer Res. 2020. PMID: 31645352 Free PMC article.

6

Cisplatin Alters Antitumor Immunity and Synergizes with PD-1/PD-L1 Inhibition in Head and Neck Squamous Cell Carcinoma.

Tran L, Allen CT, Xiao R, Moore E, Davis R, Park SJ, Spielbauer K, Van Waes C, Schmitt NC. Tran L, et al. Cancer Immunol Res. 2017 Dec;5(12):1141-1151. doi: 10.1158/2326-6066.CIR-17-0235. Epub 2017 Nov 2. Cancer Immunol Res. 2017. PMID: 29097421 Free PMC article.

7

WEE1 kinase inhibition reverses G2/M cell cycle checkpoint activation to sensitize cancer cells to immunotherapy.

Sun L, Moore E, Berman R, Clavijo PE, Saleh A, Chen Z, Van Waes C, Davies J, Friedman J, Allen CT. Sun L, et al. Oncoimmunology. 2018 Jul 23;7(10):e1488359. doi: 10.1080/2162402X.2018.1488359. eCollection 2018. Oncoimmunology. 2018. PMID: 30288354 Free PMC article.

8

Dose-dependent enhancement of T-lymphocyte priming and CTL lysis following ionizing radiation in an engineered model of oral cancer.

Morisada M, Moore EC, Hodge R, Friedman J, Cash HA, Hodge JW, Mitchell JB, Allen CT. Morisada M, et al. Among authors: moore ec. Oral Oncol. 2017 Aug;71:87-94. doi: 10.1016/j.oraloncology.2017.06.005. Epub 2017 Jun 10. Oral Oncol. 2017. PMID: 28688697 Free PMC article.

9

Resistance to CTLA-4 checkpoint inhibition reversed through selective elimination of granulocytic myeloid cells.

Clavijo PE, Moore EC, Chen J, Davis RJ, Friedman J, Kim Y, Van Waes C, Chen Z, Allen CT. Clavijo PE, et al. Among authors: moore ec. Oncotarget. 2017 Jun 11;8(34):55804-55820. doi: 10.18632/oncotarget.18437. eCollection 2017 Aug 22. Oncotarget. 2017. PMID: 28915554 Free PMC article.

10

Nanocomplex-based TP53 gene therapy promotes anti-tumor immunity through TP53- and STING-dependent mechanisms.

Moore EC, Sun L, Clavijo PE, Friedman J, Harford JB, Saleh AD, Van Waes C, Chang EH, Allen CT. Moore EC, et al. Oncoimmunology. 2018 May 7;7(7):e1404216. doi: 10.1080/2162402X.2017.1404216. eCollection 2018. Oncoimmunology. 2018. PMID: 29900037 Free PMC article.

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