Mehta NK - Search Results

1

Enhancement of Peptide Vaccine Immunogenicity by Increasing Lymphatic Drainage and Boosting Serum Stability.

Moynihan KD, Holden RL, Mehta NK, Wang C, Karver MR, Dinter J, Liang S, Abraham W, Melo MB, Zhang AQ, Li N, Gall SL, Pentelute BL, Irvine DJ. Moynihan KD, et al. Among authors: mehta nk. Cancer Immunol Res. 2018 Sep;6(9):1025-1038. doi: 10.1158/2326-6066.CIR-17-0607. Epub 2018 Jun 18. Cancer Immunol Res. 2018. PMID: 29915023 Free PMC article.

2

Engineering New Approaches to Cancer Vaccines.

Mehta NK, Moynihan KD, Irvine DJ. Mehta NK, et al. Cancer Immunol Res. 2015 Aug;3(8):836-43. doi: 10.1158/2326-6066.CIR-15-0112. Epub 2015 Jul 8. Cancer Immunol Res. 2015. PMID: 26156157 Free PMC article. Review.

3

Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses.

Moynihan KD, Opel CF, Szeto GL, Tzeng A, Zhu EF, Engreitz JM, Williams RT, Rakhra K, Zhang MH, Rothschilds AM, Kumari S, Kelly RL, Kwan BH, Abraham W, Hu K, Mehta NK, Kauke MJ, Suh H, Cochran JR, Lauffenburger DA, Wittrup KD, Irvine DJ. Moynihan KD, et al. Among authors: mehta nk. Nat Med. 2016 Dec;22(12):1402-1410. doi: 10.1038/nm.4200. Epub 2016 Oct 24. Nat Med. 2016. PMID: 27775706 Free PMC article.

4

Temporally Programmed CD8α⁺ DC Activation Enhances Combination Cancer Immunotherapy.

Tzeng A, Kauke MJ, Zhu EF, Moynihan KD, Opel CF, Yang NJ, Mehta N, Kelly RL, Szeto GL, Overwijk WW, Irvine DJ, Wittrup KD. Tzeng A, et al. Cell Rep. 2016 Dec 6;17(10):2503-2511. doi: 10.1016/j.celrep.2016.11.020. Cell Rep. 2016. PMID: 27926855 Free PMC article.

5

Order of administration of combination cytokine therapies can decouple toxicity from efficacy in syngeneic mouse tumor models.

Rothschilds A, Tzeng A, Mehta NK, Moynihan KD, Irvine DJ, Wittrup KD. Rothschilds A, et al. Among authors: mehta nk. Oncoimmunology. 2019 Feb 19;8(5):e1558678. doi: 10.1080/2162402X.2018.1558678. eCollection 2019. Oncoimmunology. 2019. PMID: 31069130 Free PMC article.

6

Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy.

Momin N, Mehta NK, Bennett NR, Ma L, Palmeri JR, Chinn MM, Lutz EA, Kang B, Irvine DJ, Spranger S, Wittrup KD. Momin N, et al. Among authors: mehta nk. Sci Transl Med. 2019 Jun 26;11(498):eaaw2614. doi: 10.1126/scitranslmed.aaw2614. Sci Transl Med. 2019. PMID: 31243150 Free PMC article.

7

Enhanced CAR-T cell activity against solid tumors by vaccine boosting through the chimeric receptor.

Ma L, Dichwalkar T, Chang JYH, Cossette B, Garafola D, Zhang AQ, Fichter M, Wang C, Liang S, Silva M, Kumari S, Mehta NK, Abraham W, Thai N, Li N, Wittrup KD, Irvine DJ. Ma L, et al. Among authors: mehta nk. Science. 2019 Jul 12;365(6449):162-168. doi: 10.1126/science.aav8692. Science. 2019. PMID: 31296767 Free PMC article.

8

Pharmacokinetic tuning of protein-antigen fusions enhances the immunogenicity of T-cell vaccines.

Mehta NK, Pradhan RV, Soleimany AP, Moynihan KD, Rothschilds AM, Momin N, Rakhra K, Mata-Fink J, Bhatia SN, Wittrup KD, Irvine DJ. Mehta NK, et al. Nat Biomed Eng. 2020 Jun;4(6):636-648. doi: 10.1038/s41551-020-0563-4. Epub 2020 Jun 1. Nat Biomed Eng. 2020. PMID: 32483299 Free PMC article.

9

Cell-penetrating peptides enhance peptide vaccine accumulation and persistence in lymph nodes to drive immunogenicity.

Backlund CM, Holden RL, Moynihan KD, Garafola D, Farquhar C, Mehta NK, Maiorino L, Pham S, Iorgulescu JB, Reardon DA, Wu CJ, Pentelute BL, Irvine DJ. Backlund CM, et al. Among authors: mehta nk. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2204078119. doi: 10.1073/pnas.2204078119. Epub 2022 Aug 1. Proc Natl Acad Sci U S A. 2022. PMID: 35914154 Free PMC article.

10

Co-Anchoring of Engineered Immunogen and Immunostimulatory Cytokines to Alum Promotes Enhanced-Humoral Immunity.

Chang JYH, Agarwal Y, Rodrigues KA, Momin N, Ni K, Read BJ, Moyer TJ, Mehta NK, Silva M, Suh H, Melo MB, Wittrup KD, Irvine DJ. Chang JYH, et al. Among authors: mehta nk. Adv Ther (Weinh). 2022 Jul;5(7):2100235. doi: 10.1002/adtp.202100235. Epub 2022 Apr 7. Adv Ther (Weinh). 2022. PMID: 36311814 Free PMC article.

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