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Page 1
Gene Editing on Center Stage.
Bak RO, Gomez-Ospina N, Porteus MH. Bak RO, et al. Among authors: porteus mh. Trends Genet. 2018 Aug;34(8):600-611. doi: 10.1016/j.tig.2018.05.004. Epub 2018 Jun 13. Trends Genet. 2018. PMID: 29908711 Review.
Gene editing: not just for translation anymore.
McMahon MA, Rahdar M, Porteus M. McMahon MA, et al. Nat Methods. 2011 Dec 28;9(1):28-31. doi: 10.1038/nmeth.1811. Nat Methods. 2011. PMID: 22205513 No abstract available.
Quantifying on- and off-target genome editing.
Hendel A, Fine EJ, Bao G, Porteus MH. Hendel A, et al. Among authors: porteus mh. Trends Biotechnol. 2015 Feb;33(2):132-40. doi: 10.1016/j.tibtech.2014.12.001. Epub 2015 Jan 13. Trends Biotechnol. 2015. PMID: 25595557 Free PMC article. Review.
Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells.
Hendel A, Bak RO, Clark JT, Kennedy AB, Ryan DE, Roy S, Steinfeld I, Lunstad BD, Kaiser RJ, Wilkens AB, Bacchetta R, Tsalenko A, Dellinger D, Bruhn L, Porteus MH. Hendel A, et al. Among authors: porteus mh. Nat Biotechnol. 2015 Sep;33(9):985-989. doi: 10.1038/nbt.3290. Epub 2015 Jun 29. Nat Biotechnol. 2015. PMID: 26121415 Free PMC article.
Genome Editing: A New Approach to Human Therapeutics.
Porteus M. Porteus M. Annu Rev Pharmacol Toxicol. 2016;56:163-90. doi: 10.1146/annurev-pharmtox-010814-124454. Epub 2015 Nov 9. Annu Rev Pharmacol Toxicol. 2016. PMID: 26566154 Review.
Mutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasis.
Gomez-Ospina N, Potter CJ, Xiao R, Manickam K, Kim MS, Kim KH, Shneider BL, Picarsic JL, Jacobson TA, Zhang J, He W, Liu P, Knisely AS, Finegold MJ, Muzny DM, Boerwinkle E, Lupski JR, Plon SE, Gibbs RA, Eng CM, Yang Y, Washington GC, Porteus MH, Berquist WE, Kambham N, Singh RJ, Xia F, Enns GM, Moore DD. Gomez-Ospina N, et al. Among authors: porteus mh. Nat Commun. 2016 Feb 18;7:10713. doi: 10.1038/ncomms10713. Nat Commun. 2016. PMID: 26888176 Free PMC article.
192 results