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In vitro and in vivo studies of gold(I) azolate/phosphane complexes for the treatment of basal like breast cancer.
Gambini V, Tilio M, Maina EW, Andreani C, Bartolacci C, Wang J, Iezzi M, Ferraro S, Ramadori AT, Simon OC, Pucciarelli S, Wu G, Dou QP, Marchini C, Galassi R, Amici A. Gambini V, et al. Among authors: pucciarelli s. Eur J Med Chem. 2018 Jul 15;155:418-427. doi: 10.1016/j.ejmech.2018.06.002. Epub 2018 Jun 2. Eur J Med Chem. 2018. PMID: 29906688
Sanguinarine suppresses basal-like breast cancer growth through dihydrofolate reductase inhibition.
Kalogris C, Garulli C, Pietrella L, Gambini V, Pucciarelli S, Lucci C, Tilio M, Zabaleta ME, Bartolacci C, Andreani C, Giangrossi M, Iezzi M, Belletti B, Marchini C, Amici A. Kalogris C, et al. Among authors: pucciarelli s. Biochem Pharmacol. 2014 Aug 1;90(3):226-34. doi: 10.1016/j.bcp.2014.05.014. Epub 2014 May 27. Biochem Pharmacol. 2014. PMID: 24875448
A study on the inhibition of dihydrofolate reductase (DHFR) from Escherichia coli by gold(i) phosphane compounds. X-ray crystal structures of (4,5-dichloro-1H-imidazolate-1-yl)-triphenylphosphane-gold(i) and (4,5-dicyano-1H-imidazolate-1-yl)-triphenylphosphane-gold(i).
Galassi R, Oumarou CS, Burini A, Dolmella A, Micozzi D, Vincenzetti S, Pucciarelli S. Galassi R, et al. Among authors: pucciarelli s. Dalton Trans. 2015 Feb 21;44(7):3043-56. doi: 10.1039/c4dt01542h. Dalton Trans. 2015. PMID: 25567238
Acetylshikonin isolated from Lithospermum erythrorhizon roots inhibits dihydrofolate reductase and hampers autochthonous mammary carcinogenesis in Δ16HER2 transgenic mice.
Wang J, Iannarelli R, Pucciarelli S, Laudadio E, Galeazzi R, Giangrossi M, Falconi M, Cui L, Navia AM, Buccioni M, Marucci G, Tomassoni D, Serini L, Sut S, Maggi F, Dall'Acqua S, Marchini C, Amici A. Wang J, et al. Among authors: pucciarelli s. Pharmacol Res. 2020 Nov;161:105123. doi: 10.1016/j.phrs.2020.105123. Epub 2020 Aug 19. Pharmacol Res. 2020. PMID: 32822867
370 results