Wang J - Search Results

1

Berberine suppresses apoptosis and extracellular matrix (ECM) degradation in nucleus pulposus cells and ameliorates disc degeneration in a rodent model.

Chen Y, Zheng Z, Wang J, Tang C, Khor S, Chen J, Chen X, Zhang Z, Tang Q, Wang C, Lou Y, Wang Z, Xiao J, Wang X. Chen Y, et al. Among authors: wang x, wang j, wang z, wang c. Int J Biol Sci. 2018 Apr 30;14(6):682-692. doi: 10.7150/ijbs.24081. eCollection 2018. Int J Biol Sci. 2018. PMID: 29904282 Free PMC article.

2

Sirt6 overexpression suppresses senescence and apoptosis of nucleus pulposus cells by inducing autophagy in a model of intervertebral disc degeneration.

Chen J, Xie JJ, Jin MY, Gu YT, Wu CC, Guo WJ, Yan YZ, Zhang ZJ, Wang JL, Zhang XL, Lin Y, Sun JL, Zhu GH, Wang XY, Wu YS. Chen J, et al. Among authors: wang jl, wang xy. Cell Death Dis. 2018 Jan 19;9(2):56. doi: 10.1038/s41419-017-0085-5. Cell Death Dis. 2018. PMID: 29352194 Free PMC article.

3

Melatonin ameliorates intervertebral disc degeneration via the potential mechanisms of mitophagy induction and apoptosis inhibition.

Chen Y, Wu Y, Shi H, Wang J, Zheng Z, Chen J, Chen X, Zhang Z, Xu D, Wang X, Xiao J. Chen Y, et al. Among authors: wang x, wang j. J Cell Mol Med. 2019 Mar;23(3):2136-2148. doi: 10.1111/jcmm.14125. Epub 2019 Jan 4. J Cell Mol Med. 2019. PMID: 30609271 Free PMC article.

4

Hydrogen sulfide protects against endoplasmic reticulum stress and mitochondrial injury in nucleus pulposus cells and ameliorates intervertebral disc degeneration.

Xu D, Jin H, Wen J, Chen J, Chen D, Cai N, Wang Y, Wang J, Chen Y, Zhang X, Wang X. Xu D, et al. Among authors: wang x, wang j, wang y. Pharmacol Res. 2017 Mar;117:357-369. doi: 10.1016/j.phrs.2017.01.005. Epub 2017 Jan 10. Pharmacol Res. 2017. PMID: 28087442

5

Therapeutic Potential of Naringin for Intervertebral Disc Degeneration: Involvement of Autophagy Against Oxidative Stress-Induced Apoptosis in Nucleus Pulposus Cells.

Zhang Z, Wang C, Lin J, Jin H, Wang K, Yan Y, Wang J, Wu C, Nisar M, Tian N, Wang X, Zhang X. Zhang Z, et al. Among authors: wang x, wang k, wang j, wang c. Am J Chin Med. 2018 Oct 4:1-20. doi: 10.1142/S0192415X18500805. Online ahead of print. Am J Chin Med. 2018. PMID: 30284462

6

Polydatin suppresses nucleus pulposus cell senescence, promotes matrix homeostasis and attenuates intervertebral disc degeneration in rats.

Wang J, Huang C, Lin Z, Pan X, Chen J, Zheng G, Tian N, Yan Y, Zhang Z, Hu J, Cheng P, Wang X, Zhang X. Wang J, et al. Among authors: wang x. J Cell Mol Med. 2018 Nov;22(11):5720-5731. doi: 10.1111/jcmm.13848. Epub 2018 Aug 30. J Cell Mol Med. 2018. PMID: 30358118 Free PMC article.

7

SIRT3 Activation by Dihydromyricetin Suppresses Chondrocytes Degeneration via Maintaining Mitochondrial Homeostasis.

Wang J, Wang K, Huang C, Lin D, Zhou Y, Wu Y, Tian N, Fan P, Pan X, Xu D, Hu J, Zhou Y, Wang X, Zhang X. Wang J, et al. Among authors: wang x, wang k. Int J Biol Sci. 2018 Oct 20;14(13):1873-1882. doi: 10.7150/ijbs.27746. eCollection 2018. Int J Biol Sci. 2018. PMID: 30443190 Free PMC article.

8

Melatonin protects endothelial progenitor cells against AGE-induced apoptosis via autophagy flux stimulation and promotes wound healing in diabetic mice.

Jin H, Zhang Z, Wang C, Tang Q, Wang J, Bai X, Wang Q, Nisar M, Tian N, Wang Q, Mao C, Zhang X, Wang X. Jin H, et al. Among authors: wang x, wang j, wang c, wang q. Exp Mol Med. 2018 Nov 21;50(11):1-15. doi: 10.1038/s12276-018-0177-z. Exp Mol Med. 2018. PMID: 30459300 Free PMC article.

9

Baicalein Inhibits the IL-1β-Induced Inflammatory Response in Nucleus Pulposus Cells and Attenuates Disc Degeneration In vivo.

Jin H, Wang Q, Wu J, Han X, Qian T, Zhang Z, Wang J, Pan X, Wu A, Wang X. Jin H, et al. Among authors: wang x, wang j, wang q. Inflammation. 2019 Jun;42(3):1032-1044. doi: 10.1007/s10753-019-00965-8. Inflammation. 2019. PMID: 30729381

10

BRD4 inhibition regulates MAPK, NF-κB signals, and autophagy to suppress MMP-13 expression in diabetic intervertebral disc degeneration.

Wang J, Hu J, Chen X, Huang C, Lin J, Shao Z, Gu M, Wu Y, Tian N, Gao W, Zhou Y, Wang X, Zhang X. Wang J, et al. Among authors: wang x. FASEB J. 2019 Oct;33(10):11555-11566. doi: 10.1096/fj.201900703R. Epub 2019 Jul 22. FASEB J. 2019. PMID: 31331201

Our study demonstrates that inhibition of BRD4 may suppress MAPK and NF-kappaB signaling and activate autophagy to suppress MMP-13 expression in diabetic IVDD, and diabetic IVDD may be compromised by BRD4 inhibitors.-Wang, J., Hu, J., Chen, X., Huang, C., Lin …

Our study demonstrates that inhibition of BRD4 may suppress MAPK and NF-kappaB signaling and activate autophagy to suppress MMP-13 expressio …

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