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Smoke-induced neuromuscular junction degeneration precedes the fibre type shift and atrophy in chronic obstructive pulmonary disease.
Kapchinsky S, Vuda M, Miguez K, Elkrief D, de Souza AR, Baglole CJ, Aare S, MacMillan NJ, Baril J, Rozakis P, Sonjak V, Pion C, Aubertin-Leheudre M, Morais JA, Jagoe RT, Bourbeau J, Taivassalo T, Hepple RT. Kapchinsky S, et al. Among authors: jagoe rt. J Physiol. 2018 Jul;596(14):2865-2881. doi: 10.1113/JP275558. Epub 2018 May 19. J Physiol. 2018. PMID: 29663403 Free PMC article.
Denervation drives mitochondrial dysfunction in skeletal muscle of octogenarians.
Spendiff S, Vuda M, Gouspillou G, Aare S, Perez A, Morais JA, Jagoe RT, Filion ME, Glicksman R, Kapchinsky S, MacMillan NJ, Pion CH, Aubertin-Leheudre M, Hettwer S, Correa JA, Taivassalo T, Hepple RT. Spendiff S, et al. Among authors: jagoe rt. J Physiol. 2016 Dec 15;594(24):7361-7379. doi: 10.1113/JP272487. Epub 2016 Oct 23. J Physiol. 2016. PMID: 27619626 Free PMC article.
Chronic aryl hydrocarbon receptor activity phenocopies smoking-induced skeletal muscle impairment.
Thome T, Miguez K, Willms AJ, Burke SK, Chandran V, de Souza AR, Fitzgerald LF, Baglole C, Anagnostou ME, Bourbeau J, Jagoe RT, Morais JA, Goddard Y, Taivassalo T, Ryan TE, Hepple RT. Thome T, et al. Among authors: jagoe rt. J Cachexia Sarcopenia Muscle. 2022 Feb;13(1):589-604. doi: 10.1002/jcsm.12826. Epub 2021 Nov 1. J Cachexia Sarcopenia Muscle. 2022. PMID: 34725955 Free PMC article.
Anthracycline-containing chemotherapy causes long-term impairment of mitochondrial respiration and increased reactive oxygen species release in skeletal muscle.
Gouspillou G, Scheede-Bergdahl C, Spendiff S, Vuda M, Meehan B, Mlynarski H, Archer-Lahlou E, Sgarioto N, Purves-Smith FM, Konokhova Y, Rak J, Chevalier S, Taivassalo T, Hepple RT, Jagoe RT. Gouspillou G, et al. Among authors: jagoe rt. Sci Rep. 2015 Mar 3;5:8717. doi: 10.1038/srep08717. Sci Rep. 2015. PMID: 25732599 Free PMC article.
37 results