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GMP-Grade Manufacturing of T Cells Engineered to Express a Defined γδTCR.
Straetemans T, Kierkels GJJ, Doorn R, Jansen K, Heijhuurs S, Dos Santos JM, van Muyden ADD, Vie H, Clemenceau B, Raymakers R, de Witte M, Sebestyén Z, Kuball J. Straetemans T, et al. Front Immunol. 2018 May 30;9:1062. doi: 10.3389/fimmu.2018.01062. eCollection 2018. Front Immunol. 2018. PMID: 29899740 Free PMC article.
γ9 and δ2CDR3 domains regulate functional avidity of T cells harboring γ9δ2TCRs.
Gründer C, van Dorp S, Hol S, Drent E, Straetemans T, Heijhuurs S, Scholten K, Scheper W, Sebestyen Z, Martens A, Strong R, Kuball J. Gründer C, et al. Among authors: straetemans t. Blood. 2012 Dec 20;120(26):5153-62. doi: 10.1182/blood-2012-05-432427. Epub 2012 Sep 27. Blood. 2012. PMID: 23018643 Free article.
Orchestrating an immune response against cancer with engineered immune cells expressing αβTCRs, CARs, and innate immune receptors: an immunological and regulatory challenge.
de Witte MA, Kierkels GJ, Straetemans T, Britten CM, Kuball J. de Witte MA, et al. Among authors: straetemans t. Cancer Immunol Immunother. 2015 Jul;64(7):893-902. doi: 10.1007/s00262-015-1710-8. Epub 2015 May 20. Cancer Immunol Immunother. 2015. PMID: 25990073 Free PMC article. Review.
Untouched GMP-Ready Purified Engineered Immune Cells to Treat Cancer.
Straetemans T, Gründer C, Heijhuurs S, Hol S, Slaper-Cortenbach I, Bönig H, Sebestyen Z, Kuball J. Straetemans T, et al. Clin Cancer Res. 2015 Sep 1;21(17):3957-68. doi: 10.1158/1078-0432.CCR-14-2860. Epub 2015 May 19. Clin Cancer Res. 2015. PMID: 25991821
The next step toward GMP-grade production of engineered immune cells.
Kierkels GJ, Straetemans T, de Witte MA, Kuball J. Kierkels GJ, et al. Among authors: straetemans t. Oncoimmunology. 2015 Aug 27;5(2):e1076608. doi: 10.1080/2162402X.2015.1076608. eCollection 2016 Feb. Oncoimmunology. 2015. PMID: 27057450 Free PMC article.
29 results