Posner BA - Search Results

1

High-Throughput Screens To Identify Autophagy Inducers That Function by Disrupting Beclin 1/Bcl-2 Binding.

Chiang WC, Wei Y, Kuo YC, Wei S, Zhou A, Zou Z, Yehl J, Ranaghan MJ, Skepner A, Bittker JA, Perez JR, Posner BA, Levine B. Chiang WC, et al. Among authors: posner ba. ACS Chem Biol. 2018 Aug 17;13(8):2247-2260. doi: 10.1021/acschembio.8b00421. Epub 2018 Jun 21. ACS Chem Biol. 2018. PMID: 29878747 Free PMC article.

2

Chromomycin SA analogs from a marine-derived Streptomyces sp.

Hu Y, Espindola AP, Stewart NA, Wei S, Posner BA, MacMillan JB. Hu Y, et al. Among authors: posner ba. Bioorg Med Chem. 2011 Sep 1;19(17):5183-9. doi: 10.1016/j.bmc.2011.07.013. Epub 2011 Jul 20. Bioorg Med Chem. 2011. PMID: 21807523 Free PMC article.

3

Identification of DNMT1 selective antagonists using a novel scintillation proximity assay.

Kilgore JA, Du X, Melito L, Wei S, Wang C, Chin HG, Posner B, Pradhan S, Ready JM, Williams NS. Kilgore JA, et al. J Biol Chem. 2013 Jul 5;288(27):19673-84. doi: 10.1074/jbc.M112.443895. Epub 2013 May 13. J Biol Chem. 2013. PMID: 23671287 Free PMC article.

4

Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer.

Kim HS, Mendiratta S, Kim J, Pecot CV, Larsen JE, Zubovych I, Seo BY, Kim J, Eskiocak B, Chung H, McMillan E, Wu S, De Brabander J, Komurov K, Toombs JE, Wei S, Peyton M, Williams N, Gazdar AF, Posner BA, Brekken RA, Sood AK, Deberardinis RJ, Roth MG, Minna JD, White MA. Kim HS, et al. Among authors: posner ba. Cell. 2013 Oct 24;155(3):552-66. doi: 10.1016/j.cell.2013.09.041. Epub 2013 Oct 24. Cell. 2013. PMID: 24243015 Free PMC article.

5

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia.

Liu Y, Shoji-Kawata S, Sumpter RM Jr, Wei Y, Ginet V, Zhang L, Posner B, Tran KA, Green DR, Xavier RJ, Shaw SY, Clarke PG, Puyal J, Levine B. Liu Y, et al. Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20364-71. doi: 10.1073/pnas.1319661110. Epub 2013 Nov 25. Proc Natl Acad Sci U S A. 2013. PMID: 24277826 Free PMC article.

6

Preclinical therapeutic efficacy of a novel pharmacologic inducer of apoptosis in malignant peripheral nerve sheath tumors.

Chau V, Lim SK, Mo W, Liu C, Patel AJ, McKay RM, Wei S, Posner BA, De Brabander JK, Williams NS, Parada LF, Le LQ. Chau V, et al. Among authors: posner ba. Cancer Res. 2014 Jan 15;74(2):586-97. doi: 10.1158/0008-5472.CAN-13-1934. Epub 2013 Nov 27. Cancer Res. 2014. PMID: 24285727 Free PMC article.

7

Streptomycin potency is dependent on MscL channel expression.

Iscla I, Wray R, Wei S, Posner B, Blount P. Iscla I, et al. Nat Commun. 2014 Sep 10;5:4891. doi: 10.1038/ncomms5891. Nat Commun. 2014. PMID: 25205267 Free PMC article.

8

GSK-3 modulates cellular responses to a broad spectrum of kinase inhibitors.

Thorne CA, Wichaidit C, Coster AD, Posner BA, Wu LF, Altschuler SJ. Thorne CA, et al. Among authors: posner ba. Nat Chem Biol. 2015 Jan;11(1):58-63. doi: 10.1038/nchembio.1690. Epub 2014 Nov 17. Nat Chem Biol. 2015. PMID: 25402767 Free PMC article.

9

An AlphaScreen Assay for the Discovery of Synthetic Chemical Inhibitors of Glucagon Production.

Evans MR, Wei S, Posner BA, Unger RH, Roth MG. Evans MR, et al. Among authors: posner ba. J Biomol Screen. 2016 Apr;21(4):325-32. doi: 10.1177/1087057115622201. Epub 2015 Dec 16. J Biomol Screen. 2016. PMID: 26676097 Free PMC article.

10

Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells.

Ramirez M, Rajaram S, Steininger RJ, Osipchuk D, Roth MA, Morinishi LS, Evans L, Ji W, Hsu CH, Thurley K, Wei S, Zhou A, Koduru PR, Posner BA, Wu LF, Altschuler SJ. Ramirez M, et al. Among authors: posner ba. Nat Commun. 2016 Feb 19;7:10690. doi: 10.1038/ncomms10690. Nat Commun. 2016. PMID: 26891683 Free PMC article.

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