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Selective pharmacological inhibition of DDR1 prevents experimentally-induced glomerulonephritis in prevention and therapeutic regime.
Moll S, Yasui Y, Abed A, Murata T, Shimada H, Maeda A, Fukushima N, Kanamori M, Uhles S, Badi L, Cagarelli T, Formentini I, Drawnel F, Georges G, Bergauer T, Gasser R, Bonfil RD, Fridman R, Richter H, Funk J, Moeller MJ, Chatziantoniou C, Prunotto M. Moll S, et al. Among authors: moeller mj. J Transl Med. 2018 Jun 1;16(1):148. doi: 10.1186/s12967-018-1524-5. J Transl Med. 2018. PMID: 29859097 Free PMC article.
DDR1 role in fibrosis and its pharmacological targeting.
Moll S, Desmoulière A, Moeller MJ, Pache JC, Badi L, Arcadu F, Richter H, Satz A, Uhles S, Cavalli A, Drawnel F, Scapozza L, Prunotto M. Moll S, et al. Among authors: moeller mj. Biochim Biophys Acta Mol Cell Res. 2019 Nov;1866(11):118474. doi: 10.1016/j.bbamcr.2019.04.004. Epub 2019 Apr 5. Biochim Biophys Acta Mol Cell Res. 2019. PMID: 30954571 Free article. Review.
Inhibition of the glucocorticoid receptor attenuates proteinuric kidney diseases in multiple species.
Stamellou E, Agrawal S, Siegerist F, Buse M, Kuppe C, Lange T, Buhl EM, Alam J, Strieder T, Boor P, Ostendorf T, Gröne HJ, Floege J, Smoyer WE, Endlich N, Moeller MJ. Stamellou E, et al. Among authors: moeller mj. Nephrol Dial Transplant. 2024 Jun 28;39(7):1181-1193. doi: 10.1093/ndt/gfad254. Nephrol Dial Transplant. 2024. PMID: 38037533 Free PMC article.
Intensive Supportive Care plus Immunosuppression in IgA Nephropathy.
Rauen T, Eitner F, Fitzner C, Sommerer C, Zeier M, Otte B, Panzer U, Peters H, Benck U, Mertens PR, Kuhlmann U, Witzke O, Gross O, Vielhauer V, Mann JF, Hilgers RD, Floege J; STOP-IgAN Investigators. Rauen T, et al. N Engl J Med. 2015 Dec 3;373(23):2225-36. doi: 10.1056/NEJMoa1415463. N Engl J Med. 2015. PMID: 26630142 Free article. Clinical Trial.
Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy.
Madhusudhan T, Wang H, Dong W, Ghosh S, Bock F, Thangapandi VR, Ranjan S, Wolter J, Kohli S, Shahzad K, Heidel F, Krueger M, Schwenger V, Moeller MJ, Kalinski T, Reiser J, Chavakis T, Isermann B. Madhusudhan T, et al. Among authors: moeller mj. Nat Commun. 2015 Mar 10;6:6496. doi: 10.1038/ncomms7496. Nat Commun. 2015. PMID: 25754093 Free PMC article.
Podocyte Integrin-β3 and Activated Protein C Coordinately Restrict RhoA Signaling and Ameliorate Diabetic Nephropathy.
Madhusudhan T, Ghosh S, Wang H, Dong W, Gupta D, Elwakiel A, Stoyanov S, Al-Dabet MM, Krishnan S, Biemann R, Nazir S, Zimmermann S, Mathew A, Gadi I, Rana R, Zeng-Brouwers J, Moeller MJ, Schaefer L, Esmon CT, Kohli S, Reiser J, Rezaie AR, Ruf W, Isermann B. Madhusudhan T, et al. Among authors: moeller mj. J Am Soc Nephrol. 2020 Aug;31(8):1762-1780. doi: 10.1681/ASN.2019111163. Epub 2020 Jul 24. J Am Soc Nephrol. 2020. PMID: 32709711 Free PMC article.
Lineage tracing reveals transient phenotypic adaptation of tubular cells during acute kidney injury.
Buse M, Cheng M, Jankowski V, Lellig M, Sterzer V, Strieder T, Leuchtle K, Martin IV, Seikrit C, Brinkkoettter P, Crispatzu G, Floege J, Boor P, Speer T, Kramann R, Ostendorf T, Moeller MJ, Costa IG, Stamellou E. Buse M, et al. Among authors: moeller mj. iScience. 2024 Feb 16;27(3):109255. doi: 10.1016/j.isci.2024.109255. eCollection 2024 Mar 15. iScience. 2024. PMID: 38444605 Free PMC article.
Human scattered tubular cells represent a heterogeneous population of glycolytic dedifferentiated proximal tubule cells.
Eymael J, van den Broek M, Miesen L, Monge VV, van den Berge BT, Mooren F, Velez VL, Dijkstra J, Hermsen M, Bándi P, Vermeulen M, de Wildt S, Willemsen B, Florquin S, Wetzels R, Steenbergen E, Kramann R, Moeller M, Schreuder MF, Wetzels JF, van der Vlag J, Jansen J, Smeets B. Eymael J, et al. J Pathol. 2023 Feb;259(2):149-162. doi: 10.1002/path.6029. Epub 2022 Dec 19. J Pathol. 2023. PMID: 36373978 Free PMC article.
120 results