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Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development.
Abramsson A, Kurup S, Busse M, Yamada S, Lindblom P, Schallmeiner E, Stenzel D, Sauvaget D, Ledin J, Ringvall M, Landegren U, Kjellén L, Bondjers G, Li JP, Lindahl U, Spillmann D, Betsholtz C, Gerhardt H. Abramsson A, et al. Among authors: betsholtz c. Genes Dev. 2007 Feb 1;21(3):316-31. doi: 10.1101/gad.398207. Genes Dev. 2007. PMID: 17289920 Free PMC article.
Pericytes regulate the blood-brain barrier.
Armulik A, Genové G, Mäe M, Nisancioglu MH, Wallgard E, Niaudet C, He L, Norlin J, Lindblom P, Strittmatter K, Johansson BR, Betsholtz C. Armulik A, et al. Among authors: betsholtz c. Nature. 2010 Nov 25;468(7323):557-61. doi: 10.1038/nature09522. Epub 2010 Oct 13. Nature. 2010. PMID: 20944627
Differential endothelial transcriptomics identifies semaphorin 3G as a vascular class 3 semaphorin.
Kutschera S, Weber H, Weick A, De Smet F, Genove G, Takemoto M, Prahst C, Riedel M, Mikelis C, Baulande S, Champseix C, Kummerer P, Conseiller E, Multon MC, Heroult M, Bicknell R, Carmeliet P, Betsholtz C, Augustin HG. Kutschera S, et al. Among authors: betsholtz c. Arterioscler Thromb Vasc Biol. 2011 Jan;31(1):151-9. doi: 10.1161/ATVBAHA.110.215871. Epub 2010 Oct 14. Arterioscler Thromb Vasc Biol. 2011. PMID: 20947821
The sphingosine-1-phosphate receptor S1PR1 restricts sprouting angiogenesis by regulating the interplay between VE-cadherin and VEGFR2.
Gaengel K, Niaudet C, Hagikura K, Laviña B, Muhl L, Hofmann JJ, Ebarasi L, Nyström S, Rymo S, Chen LL, Pang MF, Jin Y, Raschperger E, Roswall P, Schulte D, Benedito R, Larsson J, Hellström M, Fuxe J, Uhlén P, Adams R, Jakobsson L, Majumdar A, Vestweber D, Uv A, Betsholtz C. Gaengel K, et al. Among authors: betsholtz c. Dev Cell. 2012 Sep 11;23(3):587-99. doi: 10.1016/j.devcel.2012.08.005. Dev Cell. 2012. PMID: 22975327 Free article.
351 results