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Discovery of a Potent Kelch-Like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 (Keap1-Nrf2) Protein-Protein Interaction Inhibitor with Natural Proline Structure as a Cytoprotective Agent against Acetaminophen-Induced Hepatotoxicity.
Lu MC, Zhang X, Wu F, Tan SJ, Zhao J, You QD, Jiang ZY. Lu MC, et al. Among authors: zhang x. J Med Chem. 2019 Jul 25;62(14):6796-6813. doi: 10.1021/acs.jmedchem.9b00818. Epub 2019 Jul 17. J Med Chem. 2019. PMID: 31283229
Non-small molecule PROTACs (NSM-PROTACs): Protein degradation kaleidoscope.
Ma S, Ji J, Tong Y, Zhu Y, Dou J, Zhang X, Xu S, Zhu T, Xu X, You Q, Jiang Z. Ma S, et al. Among authors: zhang x. Acta Pharm Sin B. 2022 Jul;12(7):2990-3005. doi: 10.1016/j.apsb.2022.02.022. Epub 2022 Feb 26. Acta Pharm Sin B. 2022. PMID: 35865099 Free PMC article. Review.
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