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Aldehyde dehydrogenase 3A1 activation prevents radiation-induced xerostomia by protecting salivary stem cells from toxic aldehydes.
Saiki JP, Cao H, Van Wassenhove LD, Viswanathan V, Bloomstein J, Nambiar DK, Mattingly AJ, Jiang D, Chen CH, Stevens MC, Simmons AL, Park HS, von Eyben R, Kool ET, Sirjani D, Knox SM, Le QT, Mochly-Rosen D. Saiki JP, et al. Among authors: stevens mc. Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):6279-6284. doi: 10.1073/pnas.1802184115. Epub 2018 May 24. Proc Natl Acad Sci U S A. 2018. PMID: 29794221 Free PMC article.
Function through synthesis-informed design.
Wender PA, Quiroz RV, Stevens MC. Wender PA, et al. Among authors: stevens mc. Acc Chem Res. 2015 Mar 17;48(3):752-60. doi: 10.1021/acs.accounts.5b00004. Epub 2015 Mar 5. Acc Chem Res. 2015. PMID: 25742599 Free PMC article.
Function through bio-inspired, synthesis-informed design: step-economical syntheses of designed kinase inhibitors†Dedicated to Max Malacria, a friend and scholar whose science and creative contributions to step-economical synthesis have inspired us all and moved the field closer to the ideal.‡Electronic supplementary information (ESI) available: Synthetic procedures and spectral data. See DOI: 10.1039/c4qo00228hClick here for additional data file.
Wender PA, Axtman AD, Golden JE, Kee JM, Sirois LE, Quiroz RV, Stevens MC. Wender PA, et al. Among authors: stevens mc. Org Chem Front. 2014 Dec 29;1(10):1166-1171. doi: 10.1039/c4qo00228h. Epub 2014 Oct 6. Org Chem Front. 2014. PMID: 25632347 Free PMC article.
308 results