Hrycyna CA - Search Results

1

ZMPSTE24 missense mutations that cause progeroid diseases decrease prelamin A cleavage activity and/or protein stability.

Spear ED, Hsu ET, Nie L, Carpenter EP, Hrycyna CA, Michaelis S. Spear ED, et al. Among authors: hrycyna ca. Dis Model Mech. 2018 Jul 13;11(7):dmm033670. doi: 10.1242/dmm.033670. Dis Model Mech. 2018. PMID: 29794150 Free PMC article.

2

A Quantitative FRET Assay for the Upstream Cleavage Activity of the Integral Membrane Proteases Human ZMPSTE24 and Yeast Ste24.

Hsu ET, Vervacke JS, Distefano MD, Hrycyna CA. Hsu ET, et al. Among authors: hrycyna ca. Methods Mol Biol. 2019;2009:279-293. doi: 10.1007/978-1-4939-9532-5_21. Methods Mol Biol. 2019. PMID: 31152411

3

Human ZMPSTE24 disease mutations: residual proteolytic activity correlates with disease severity.

Barrowman J, Wiley PA, Hudon-Miller SE, Hrycyna CA, Michaelis S. Barrowman J, et al. Among authors: hrycyna ca. Hum Mol Genet. 2012 Sep 15;21(18):4084-93. doi: 10.1093/hmg/dds233. Epub 2012 Jun 19. Hum Mol Genet. 2012. PMID: 22718200 Free PMC article.

4

Purification, functional reconstitution, and characterization of the Saccharomyces cerevisiae isoprenylcysteine carboxylmethyltransferase Ste14p.

Anderson JL, Frase H, Michaelis S, Hrycyna CA. Anderson JL, et al. Among authors: hrycyna ca. J Biol Chem. 2005 Feb 25;280(8):7336-45. doi: 10.1074/jbc.M410292200. Epub 2004 Dec 20. J Biol Chem. 2005. PMID: 15611058 Free article.

5

HIV-protease inhibitors block the enzymatic activity of purified Ste24p.

Hudon SE, Coffinier C, Michaelis S, Fong LG, Young SG, Hrycyna CA. Hudon SE, et al. Among authors: hrycyna ca. Biochem Biophys Res Commun. 2008 Sep 19;374(2):365-8. doi: 10.1016/j.bbrc.2008.07.033. Epub 2008 Jul 17. Biochem Biophys Res Commun. 2008. PMID: 18639527 Free PMC article.

6

Biochemistry. A protease for the ages.

Michaelis S, Hrycyna CA. Michaelis S, et al. Among authors: hrycyna ca. Science. 2013 Mar 29;339(6127):1529-30. doi: 10.1126/science.1236764. Science. 2013. PMID: 23539586 No abstract available.

7

a-Factor Analogues Containing Alkyne- and Azide-Functionalized Isoprenoids Are Efficiently Enzymatically Processed and Retain Wild-Type Bioactivity.

Diaz-Rodriguez V, Hsu ET, Ganusova E, Werst ER, Becker JM, Hrycyna CA, Distefano MD. Diaz-Rodriguez V, et al. Among authors: hrycyna ca. Bioconjug Chem. 2018 Feb 21;29(2):316-323. doi: 10.1021/acs.bioconjchem.7b00648. Epub 2017 Dec 20. Bioconjug Chem. 2018. PMID: 29188996 Free PMC article.

8

Prelamin A endoproteolytic processing in vitro by recombinant Zmpste24.

Corrigan DP, Kuszczak D, Rusinol AE, Thewke DP, Hrycyna CA, Michaelis S, Sinensky MS. Corrigan DP, et al. Among authors: hrycyna ca. Biochem J. 2005 Apr 1;387(Pt 1):129-38. doi: 10.1042/BJ20041359. Biochem J. 2005. PMID: 15479156 Free PMC article.

9

Therapeutic intervention based on protein prenylation and associated modifications.

Gelb MH, Brunsveld L, Hrycyna CA, Michaelis S, Tamanoi F, Van Voorhis WC, Waldmann H. Gelb MH, et al. Among authors: hrycyna ca. Nat Chem Biol. 2006 Oct;2(10):518-28. doi: 10.1038/nchembio818. Nat Chem Biol. 2006. PMID: 16983387 Free PMC article. Review.

10

The Saccharomyces cerevisiae STE14 gene encodes a methyltransferase that mediates C-terminal methylation of a-factor and RAS proteins.

Hrycyna CA, Sapperstein SK, Clarke S, Michaelis S. Hrycyna CA, et al. EMBO J. 1991 Jul;10(7):1699-709. doi: 10.1002/j.1460-2075.1991.tb07694.x. EMBO J. 1991. PMID: 2050108 Free PMC article.

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