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Integrated time course omics analysis distinguishes immediate therapeutic response from acquired resistance.
Stein-O'Brien G, Kagohara LT, Li S, Thakar M, Ranaweera R, Ozawa H, Cheng H, Considine M, Schmitz S, Favorov AV, Danilova LV, Califano JA, Izumchenko E, Gaykalova DA, Chung CH, Fertig EJ. Stein-O'Brien G, et al. Among authors: izumchenko e. Genome Med. 2018 May 23;10(1):37. doi: 10.1186/s13073-018-0545-2. Genome Med. 2018. PMID: 29792227 Free PMC article.
Cleaved NOTCH1 Expression Pattern in Head and Neck Squamous Cell Carcinoma Is Associated with NOTCH1 Mutation, HPV Status, and High-Risk Features.
Rettig EM, Chung CH, Bishop JA, Howard JD, Sharma R, Li RJ, Douville C, Karchin R, Izumchenko E, Sidransky D, Koch W, Califano J, Agrawal N, Fakhry C. Rettig EM, et al. Among authors: izumchenko e. Cancer Prev Res (Phila). 2015 Apr;8(4):287-95. doi: 10.1158/1940-6207.CAPR-14-0366. Epub 2015 Jan 29. Cancer Prev Res (Phila). 2015. PMID: 25633867 Free PMC article.
Comparative mutational landscape analysis of patient-derived tumour xenografts.
Brait M, Izumchenko E, Kagohara LT, Long S, Wysocki PT, Faherty B, Fertig EJ, Khor TO, Bruckheimer E, Baia G, Ciznadija D, Sloma I, Ben-Zvi I, Paz K, Sidransky D. Brait M, et al. Among authors: izumchenko e. Br J Cancer. 2017 Feb 14;116(4):515-523. doi: 10.1038/bjc.2016.450. Epub 2017 Jan 24. Br J Cancer. 2017. PMID: 28118322 Free PMC article.
SMAD4 Loss Is Associated with Cetuximab Resistance and Induction of MAPK/JNK Activation in Head and Neck Cancer Cells.
Ozawa H, Ranaweera RS, Izumchenko E, Makarev E, Zhavoronkov A, Fertig EJ, Howard JD, Markovic A, Bedi A, Ravi R, Perez J, Le QT, Kong CS, Jordan RC, Wang H, Kang H, Quon H, Sidransky D, Chung CH. Ozawa H, et al. Among authors: izumchenko e. Clin Cancer Res. 2017 Sep 1;23(17):5162-5175. doi: 10.1158/1078-0432.CCR-16-1686. Epub 2017 May 18. Clin Cancer Res. 2017. PMID: 28522603 Free PMC article.
In silico analysis of pathways activation landscape in oral squamous cell carcinoma and oral leukoplakia.
Makarev E, Schubert AD, Kanherkar RR, London N, Teka M, Ozerov I, Lezhnina K, Bedi A, Ravi R, Mehra R, Hoque MO, Sloma I, Gaykalova DA, Csoka AB, Sidransky D, Zhavoronkov A, Izumchenko E. Makarev E, et al. Among authors: izumchenko e. Cell Death Discov. 2017 May 22;3:17022. doi: 10.1038/cddiscovery.2017.22. eCollection 2017. Cell Death Discov. 2017. PMID: 28580171 Free PMC article.
Integrated Analysis of Whole-Genome ChIP-Seq and RNA-Seq Data of Primary Head and Neck Tumor Samples Associates HPV Integration Sites with Open Chromatin Marks.
Kelley DZ, Flam EL, Izumchenko E, Danilova LV, Wulf HA, Guo T, Singman DA, Afsari B, Skaist AM, Considine M, Welch JA, Stavrovskaya E, Bishop JA, Westra WH, Khan Z, Koch WM, Sidransky D, Wheelan SJ, Califano JA, Favorov AV, Fertig EJ, Gaykalova DA. Kelley DZ, et al. Among authors: izumchenko e. Cancer Res. 2017 Dec 1;77(23):6538-6550. doi: 10.1158/0008-5472.CAN-17-0833. Epub 2017 Sep 25. Cancer Res. 2017. PMID: 28947419 Free PMC article.
Targeting focal adhesion kinase overcomes erlotinib resistance in smoke induced lung cancer by altering phosphorylation of epidermal growth factor receptor.
Solanki HS, Raja R, Zhavoronkov A, Ozerov IV, Artemov AV, Advani J, Radhakrishnan A, Babu N, Puttamallesh VN, Syed N, Nanjappa V, Subbannayya T, Sahasrabuddhe NA, Patil AH, Prasad TSK, Gaykalova D, Chang X, Sathyendran R, Mathur PP, Rangarajan A, Sidransky D, Pandey A, Izumchenko E, Gowda H, Chatterjee A. Solanki HS, et al. Among authors: izumchenko e. Oncoscience. 2018 Feb 23;5(1-2):21-38. doi: 10.18632/oncoscience.395. eCollection 2018 Jan. Oncoscience. 2018. PMID: 29556515 Free PMC article.
82 results