Grove TL - Search Results

1

Investigation of Solvent Hydron Exchange in the Reaction Catalyzed by the Antibiotic Resistance Protein Cfr.

Bauerle MR, Grove TL, Booker SJ. Bauerle MR, et al. Among authors: grove tl. Biochemistry. 2018 Jul 31;57(30):4431-4439. doi: 10.1021/acs.biochem.8b00347. Epub 2018 Jul 23. Biochemistry. 2018. PMID: 29787246 Free PMC article.

2

A consensus mechanism for Radical SAM-dependent dehydrogenation? BtrN contains two [4Fe-4S] clusters.

Grove TL, Ahlum JH, Sharma P, Krebs C, Booker SJ. Grove TL, et al. Biochemistry. 2010 May 11;49(18):3783-5. doi: 10.1021/bi9022126. Biochemistry. 2010. PMID: 20377206 Free PMC article.

3

Cfr and RlmN contain a single [4Fe-4S] cluster, which directs two distinct reactivities for S-adenosylmethionine: methyl transfer by SN2 displacement and radical generation.

Grove TL, Radle MI, Krebs C, Booker SJ. Grove TL, et al. J Am Chem Soc. 2011 Dec 14;133(49):19586-9. doi: 10.1021/ja207327v. Epub 2011 Nov 18. J Am Chem Soc. 2011. PMID: 21916495 Free PMC article.

4

Further characterization of Cys-type and Ser-type anaerobic sulfatase maturating enzymes suggests a commonality in the mechanism of catalysis.

Grove TL, Ahlum JH, Qin RM, Lanz ND, Radle MI, Krebs C, Booker SJ. Grove TL, et al. Biochemistry. 2013 Apr 30;52(17):2874-87. doi: 10.1021/bi400136u. Epub 2013 Apr 16. Biochemistry. 2013. PMID: 23477283 Free PMC article.

5

A substrate radical intermediate in catalysis by the antibiotic resistance protein Cfr.

Grove TL, Livada J, Schwalm EL, Green MT, Booker SJ, Silakov A. Grove TL, et al. Nat Chem Biol. 2013 Jul;9(7):422-7. doi: 10.1038/nchembio.1251. Epub 2013 May 5. Nat Chem Biol. 2013. PMID: 23644479 Free PMC article.

6

Characterization of a cross-linked protein-nucleic acid substrate radical in the reaction catalyzed by RlmN.

Silakov A, Grove TL, Radle MI, Bauerle MR, Green MT, Rosenzweig AC, Boal AK, Booker SJ. Silakov A, et al. Among authors: grove tl. J Am Chem Soc. 2014 Jun 11;136(23):8221-8. doi: 10.1021/ja410560p. Epub 2014 Jun 2. J Am Chem Soc. 2014. PMID: 24806349 Free PMC article.

7

In vitro characterization of AtsB, a radical SAM formylglycine-generating enzyme that contains three [4Fe-4S] clusters.

Grove TL, Lee KH, St Clair J, Krebs C, Booker SJ. Grove TL, et al. Biochemistry. 2008 Jul 15;47(28):7523-38. doi: 10.1021/bi8004297. Epub 2008 Jun 18. Biochemistry. 2008. PMID: 18558715 Free PMC article.

8

A radically different mechanism for S-adenosylmethionine-dependent methyltransferases.

Grove TL, Benner JS, Radle MI, Ahlum JH, Landgraf BJ, Krebs C, Booker SJ. Grove TL, et al. Science. 2011 Apr 29;332(6029):604-7. doi: 10.1126/science.1200877. Epub 2011 Mar 17. Science. 2011. PMID: 21415317

9

Structural basis for methyl transfer by a radical SAM enzyme.

Boal AK, Grove TL, McLaughlin MI, Yennawar NH, Booker SJ, Rosenzweig AC. Boal AK, et al. Among authors: grove tl. Science. 2011 May 27;332(6033):1089-92. doi: 10.1126/science.1205358. Epub 2011 Apr 28. Science. 2011. PMID: 21527678 Free PMC article.

10

Crystallographic capture of a radical S-adenosylmethionine enzyme in the act of modifying tRNA.

Schwalm EL, Grove TL, Booker SJ, Boal AK. Schwalm EL, et al. Among authors: grove tl. Science. 2016 Apr 15;352(6283):309-12. doi: 10.1126/science.aad5367. Science. 2016. PMID: 27081063 Free PMC article.

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