Aharoni A - Search Results

1

Point Mutation of a Non-Elastase-Binding Site in Human α1-Antitrypsin Alters Its Anti-Inflammatory Properties.

Lior Y, Zaretsky M, Ochayon DE, Lotysh D, Baranovski BM, Schuster R, Guttman O, Aharoni A, Lewis EC. Lior Y, et al. Among authors: aharoni a. Front Immunol. 2018 May 1;9:759. doi: 10.3389/fimmu.2018.00759. eCollection 2018. Front Immunol. 2018. PMID: 29780379 Free PMC article.

2

Application of directed evolution and back-to-consensus algorithms to human alpha1-antitrypsin leads to diminished anti-protease activity and augmented anti-inflammatory activities.

Lior Y, Jasevitch M, Ochayon DE, Zaretsky M, Lewis EC, Aharoni A. Lior Y, et al. Among authors: aharoni a. Cell Immunol. 2020 Sep;355:104135. doi: 10.1016/j.cellimm.2020.104135. Epub 2020 May 21. Cell Immunol. 2020. PMID: 32703529

3

Cac1 WHD and PIP domains have distinct roles in replisome progression and genomic stability.

Tsirkas I, Dovrat D, Lei Y, Kalyva A, Lotysh D, Li Q, Aharoni A. Tsirkas I, et al. Among authors: aharoni a. Curr Genet. 2021 Feb;67(1):129-139. doi: 10.1007/s00294-020-01113-8. Epub 2020 Oct 6. Curr Genet. 2021. PMID: 33025160

4

Employing directed evolution for the functional analysis of multi-specific proteins.

Levin M, Amar D, Aharoni A. Levin M, et al. Among authors: aharoni a. Bioorg Med Chem. 2013 Jun 15;21(12):3511-6. doi: 10.1016/j.bmc.2013.04.052. Epub 2013 Apr 27. Bioorg Med Chem. 2013. PMID: 23683833 Review.

5

Directed evolution of a soluble human DR3 receptor for the inhibition of TL1A induced cytokine secretion.

Levin I, Zaretsky M, Aharoni A. Levin I, et al. Among authors: aharoni a. PLoS One. 2017 Mar 9;12(3):e0173460. doi: 10.1371/journal.pone.0173460. eCollection 2017. PLoS One. 2017. PMID: 28278297 Free PMC article.

6

Increased Potency of a Bi-specific TL1A-ADAM17 (TACE) Inhibitor by Cell Surface Targeting.

Weizman T, Levin I, Zaretsky M, Sagi I, Aharoni A. Weizman T, et al. Among authors: aharoni a. Front Mol Biosci. 2017 Aug 22;4:61. doi: 10.3389/fmolb.2017.00061. eCollection 2017. Front Mol Biosci. 2017. PMID: 28879185 Free PMC article.

7

Directed evolution of SIRT6 for improved deacylation and glucose homeostasis maintenance.

Gertman O, Omer D, Hendler A, Stein D, Onn L, Khukhin Y, Portillo M, Zarivach R, Cohen HY, Toiber D, Aharoni A. Gertman O, et al. Among authors: aharoni a. Sci Rep. 2018 Feb 23;8(1):3538. doi: 10.1038/s41598-018-21887-9. Sci Rep. 2018. PMID: 29476161 Free PMC article.

8

A Bacterial Quorum Sensing Molecule Elicits a General Stress Response in Saccharomyces cerevisiae.

Delago A, Gregor R, Dubinsky L, Dandela R, Hendler A, Krief P, Rayo J, Aharoni A, Meijler MM. Delago A, et al. Among authors: aharoni a. Front Microbiol. 2021 Sep 16;12:632658. doi: 10.3389/fmicb.2021.632658. eCollection 2021. Front Microbiol. 2021. PMID: 34603220 Free PMC article.

9

Subtle alterations in PCNA-partner interactions severely impair DNA replication and repair.

Fridman Y, Palgi N, Dovrat D, Ben-Aroya S, Hieter P, Aharoni A. Fridman Y, et al. Among authors: aharoni a. PLoS Biol. 2010 Oct 12;8(10):e1000507. doi: 10.1371/journal.pbio.1000507. PLoS Biol. 2010. PMID: 20967232 Free PMC article.

10

Proliferating cell nuclear antigen is a novel inhibitory ligand for the natural cytotoxicity receptor NKp44.

Rosental B, Brusilovsky M, Hadad U, Oz D, Appel MY, Afergan F, Yossef R, Rosenberg LA, Aharoni A, Cerwenka A, Campbell KS, Braiman A, Porgador A. Rosental B, et al. Among authors: aharoni a. J Immunol. 2011 Dec 1;187(11):5693-702. doi: 10.4049/jimmunol.1102267. Epub 2011 Oct 21. J Immunol. 2011. PMID: 22021614 Free PMC article.

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