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IL4-10 fusion protein has chondroprotective, anti-inflammatory and potentially analgesic effects in the treatment of osteoarthritis.
Steen-Louws C, Popov-Celeketic J, Mastbergen SC, Coeleveld K, Hack CE, Eijkelkamp N, Tryfonidou M, Spruijt S, van Roon JAG, Lafeber FPJG. Steen-Louws C, et al. Among authors: popov celeketic j. Osteoarthritis Cartilage. 2018 Aug;26(8):1127-1135. doi: 10.1016/j.joca.2018.05.005. Epub 2018 May 26. Osteoarthritis Cartilage. 2018. PMID: 29775732 Free article.
Development of Recombinant Proteins to Treat Chronic Pain.
Prado J, Popov-Celeketic J, Steen-Louws C, Raoof R, Hack E, Eijkelkamp N. Prado J, et al. Among authors: popov celeketic j. J Vis Exp. 2018 Apr 11;(134):57071. doi: 10.3791/57071. J Vis Exp. 2018. PMID: 29708532 Free PMC article.
Cytokine receptor clustering in sensory neurons with an engineered cytokine fusion protein triggers unique pain resolution pathways.
Prado J, Westerink RHS, Popov-Celeketic J, Steen-Louws C, Pandit A, Versteeg S, van de Worp W, Kanters DHAJ, Reedquist KA, Koenderman L, Hack CE, Eijkelkamp N. Prado J, et al. Among authors: popov celeketic j. Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):e2009647118. doi: 10.1073/pnas.2009647118. Proc Natl Acad Sci U S A. 2021. PMID: 33836560 Free PMC article.
IL4-10 Fusion Protein Shows DMOAD Activity in a Rat Osteoarthritis Model.
van Helvoort EM, de Visser HM, Lafeber FPJG, Coeleveld K, Versteeg S, Weinans HH, Popov-Celeketic J, Eijkelkamp N, Mastbergen SC. van Helvoort EM, et al. Among authors: popov celeketic j. Cartilage. 2021 Dec;13(2_suppl):1155S-1164S. doi: 10.1177/19476035211026736. Epub 2021 Jun 23. Cartilage. 2021. PMID: 34159843 Free PMC article.
The catabolic-to-anabolic shift seen in the canine osteoarthritic cartilage treated with knee joint distraction occurs after the distraction period.
Teunissen M, Meij BP, Snel L, Coeleveld K, Popov-Celeketic J, Ludwig IS, Broere F, Lafeber FPJG, Tryfonidou MA, Mastbergen SC. Teunissen M, et al. Among authors: popov celeketic j. J Orthop Translat. 2022 Oct 20;38:44-55. doi: 10.1016/j.jot.2022.09.003. eCollection 2023 Jan. J Orthop Translat. 2022. PMID: 36313973 Free PMC article.
11 results