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Multifactorial T-cell hypofunction that is reversible can limit the efficacy of chimeric antigen receptor-transduced human T cells in solid tumors.
Moon EK, Wang LC, Dolfi DV, Wilson CB, Ranganathan R, Sun J, Kapoor V, Scholler J, Puré E, Milone MC, June CH, Riley JL, Wherry EJ, Albelda SM. Moon EK, et al. Among authors: albelda sm. Clin Cancer Res. 2014 Aug 15;20(16):4262-73. doi: 10.1158/1078-0432.CCR-13-2627. Epub 2014 Jun 11. Clin Cancer Res. 2014. PMID: 24919573 Free PMC article.
Origin and Role of a Subset of Tumor-Associated Neutrophils with Antigen-Presenting Cell Features in Early-Stage Human Lung Cancer.
Singhal S, Bhojnagarwala PS, O'Brien S, Moon EK, Garfall AL, Rao AS, Quatromoni JG, Stephen TL, Litzky L, Deshpande C, Feldman MD, Hancock WW, Conejo-Garcia JR, Albelda SM, Eruslanov EB. Singhal S, et al. Among authors: albelda sm. Cancer Cell. 2016 Jul 11;30(1):120-135. doi: 10.1016/j.ccell.2016.06.001. Epub 2016 Jun 30. Cancer Cell. 2016. PMID: 27374224 Free PMC article.
CAR T Cell Therapy for Solid Tumors.
Newick K, O'Brien S, Moon E, Albelda SM. Newick K, et al. Among authors: albelda sm. Annu Rev Med. 2017 Jan 14;68:139-152. doi: 10.1146/annurev-med-062315-120245. Epub 2016 Nov 17. Annu Rev Med. 2017. PMID: 27860544 Review.
Human tumor-associated monocytes/macrophages and their regulation of T cell responses in early-stage lung cancer.
Singhal S, Stadanlick J, Annunziata MJ, Rao AS, Bhojnagarwala PS, O'Brien S, Moon EK, Cantu E, Danet-Desnoyers G, Ra HJ, Litzky L, Akimova T, Beier UH, Hancock WW, Albelda SM, Eruslanov EB. Singhal S, et al. Among authors: albelda sm. Sci Transl Med. 2019 Feb 13;11(479):eaat1500. doi: 10.1126/scitranslmed.aat1500. Sci Transl Med. 2019. PMID: 30760579 Free PMC article.
Function of Human Tumor-Infiltrating Lymphocytes in Early-Stage Non-Small Cell Lung Cancer.
O'Brien SM, Klampatsa A, Thompson JC, Martinez MC, Hwang WT, Rao AS, Standalick JE, Kim S, Cantu E, Litzky LA, Singhal S, Eruslanov EB, Moon EK, Albelda SM. O'Brien SM, et al. Among authors: albelda sm. Cancer Immunol Res. 2019 Jun;7(6):896-909. doi: 10.1158/2326-6066.CIR-18-0713. Epub 2019 May 3. Cancer Immunol Res. 2019. PMID: 31053597 Free PMC article.
Phenotypic and functional analysis of malignant mesothelioma tumor-infiltrating lymphocytes.
Klampatsa A, O'Brien SM, Thompson JC, Rao AS, Stadanlick JE, Martinez MC, Liousia M, Cantu E, Cengel K, Moon EK, Singhal S, Eruslanov EB, Albelda SM. Klampatsa A, et al. Among authors: albelda sm. Oncoimmunology. 2019 Jul 13;8(9):e1638211. doi: 10.1080/2162402X.2019.1638211. eCollection 2019. Oncoimmunology. 2019. PMID: 31428531 Free PMC article.
358 results