Scrutton NS - Search Results

1

A 'Plug and Play' Platform for the Production of Diverse Monoterpene Hydrocarbon Scaffolds in Escherichia coli.

Leferink NGH, Jervis AJ, Zebec Z, Toogood HS, Hay S, Takano E, Scrutton NS. Leferink NGH, et al. Among authors: scrutton ns. ChemistrySelect. 2016 Jun 21;1(9):1893-1896. doi: 10.1002/slct.201600563. ChemistrySelect. 2016. PMID: 29756025 Free PMC article.

2

Stabilization of non-productive conformations underpins rapid electron transfer to electron-transferring flavoprotein.

Toogood HS, van Thiel A, Scrutton NS, Leys D. Toogood HS, et al. Among authors: scrutton ns. J Biol Chem. 2005 Aug 26;280(34):30361-6. doi: 10.1074/jbc.M505562200. Epub 2005 Jun 23. J Biol Chem. 2005. PMID: 15975918 Free article.

3

Alpha-secondary isotope effects as probes of "tunneling-ready" configurations in enzymatic H-tunneling: insight from environmentally coupled tunneling models.

Pudney CR, Hay S, Sutcliffe MJ, Scrutton NS. Pudney CR, et al. Among authors: scrutton ns. J Am Chem Soc. 2006 Nov 1;128(43):14053-8. doi: 10.1021/ja0614619. J Am Chem Soc. 2006. PMID: 17061887

4

Promoting motions in enzyme catalysis probed by pressure studies of kinetic isotope effects.

Hay S, Sutcliffe MJ, Scrutton NS. Hay S, et al. Among authors: scrutton ns. Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):507-12. doi: 10.1073/pnas.0608408104. Epub 2007 Jan 3. Proc Natl Acad Sci U S A. 2007. PMID: 17202258 Free PMC article.

5

Crystal structure and solution characterization of the activation domain of human methionine synthase.

Wolthers KR, Toogood HS, Jowitt TA, Marshall KR, Leys D, Scrutton NS. Wolthers KR, et al. Among authors: scrutton ns. FEBS J. 2007 Feb;274(3):738-50. doi: 10.1111/j.1742-4658.2006.05618.x. FEBS J. 2007. PMID: 17288554 Free article.

6

Proton tunneling in aromatic amine dehydrogenase is driven by a short-range sub-picosecond promoting vibration: consistency of simulation and theory with experiment.

Johannissen LO, Hay S, Scrutton NS, Sutcliffe MJ. Johannissen LO, et al. Among authors: scrutton ns. J Phys Chem B. 2007 Mar 15;111(10):2631-8. doi: 10.1021/jp066276w. Epub 2007 Feb 17. J Phys Chem B. 2007. PMID: 17305385

7

Conformational and thermodynamic control of electron transfer in neuronal nitric oxide synthase.

Dunford AJ, Rigby SE, Hay S, Munro AW, Scrutton NS. Dunford AJ, et al. Among authors: scrutton ns. Biochemistry. 2007 May 1;46(17):5018-29. doi: 10.1021/bi7001339. Epub 2007 Apr 6. Biochemistry. 2007. PMID: 17411075

8

Conformational dynamics of the cytochrome P450 BM3/N-palmitoylglycine complex: the proposed "proximal-distal" transition probed by temperature-jump spectroscopy.

Brenner S, Hay S, Girvan HM, Munro AW, Scrutton NS. Brenner S, et al. Among authors: scrutton ns. J Phys Chem B. 2007 Jul 12;111(27):7879-86. doi: 10.1021/jp073036n. Epub 2007 Jun 16. J Phys Chem B. 2007. PMID: 17571881

9

DNA binding suppresses human AIF-M2 activity and provides a connection between redox chemistry, reactive oxygen species, and apoptosis.

Gong M, Hay S, Marshall KR, Munro AW, Scrutton NS. Gong M, et al. Among authors: scrutton ns. J Biol Chem. 2007 Oct 12;282(41):30331-40. doi: 10.1074/jbc.M703713200. Epub 2007 Aug 20. J Biol Chem. 2007. PMID: 17711848 Free article.

10

Mechanism of coenzyme binding to human methionine synthase reductase revealed through the crystal structure of the FNR-like module and isothermal titration calorimetry.

Wolthers KR, Lou X, Toogood HS, Leys D, Scrutton NS. Wolthers KR, et al. Among authors: scrutton ns. Biochemistry. 2007 Oct 23;46(42):11833-44. doi: 10.1021/bi701209p. Epub 2007 Sep 25. Biochemistry. 2007. PMID: 17892308

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