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Atomic description of an enzyme reaction dominated by proton tunneling.
Masgrau L, Roujeinikova A, Johannissen LO, Hothi P, Basran J, Ranaghan KE, Mulholland AJ, Sutcliffe MJ, Scrutton NS, Leys D. Masgrau L, et al. Among authors: scrutton ns. Science. 2006 Apr 14;312(5771):237-41. doi: 10.1126/science.1126002. Science. 2006. PMID: 16614214
Atomistic insight into the origin of the temperature-dependence of kinetic isotope effects and H-tunnelling in enzyme systems is revealed through combined experimental studies and biomolecular simulation.
Hay S, Pudney C, Hothi P, Johannissen LO, Masgrau L, Pang J, Leys D, Sutcliffe MJ, Scrutton NS. Hay S, et al. Among authors: scrutton ns. Biochem Soc Trans. 2008 Feb;36(Pt 1):16-21. doi: 10.1042/BST0360016. Biochem Soc Trans. 2008. PMID: 18208377 Review.
444 results