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Effective silencing of ENaC by siRNA delivered with epithelial-targeted nanocomplexes in human cystic fibrosis cells and in mouse lung.
Tagalakis AD, Munye MM, Ivanova R, Chen H, Smith CM, Aldossary AM, Rosa LZ, Moulding D, Barnes JL, Kafetzis KN, Jones SA, Baines DL, Moss GWJ, O'Callaghan C, McAnulty RJ, Hart SL. Tagalakis AD, et al. Among authors: kafetzis kn. Thorax. 2018 Sep;73(9):847-856. doi: 10.1136/thoraxjnl-2017-210670. Epub 2018 May 10. Thorax. 2018. PMID: 29748250 Free PMC article.
The Effect of Cryoprotectants and Storage Conditions on the Transfection Efficiency, Stability, and Safety of Lipid-Based Nanoparticles for mRNA and DNA Delivery.
Kafetzis KN, Papalamprou N, McNulty E, Thong KX, Sato Y, Mironov A, Purohit A, Welsby PJ, Harashima H, Yu-Wai-Man C, Tagalakis AD. Kafetzis KN, et al. Adv Healthc Mater. 2023 Jul;12(18):e2203022. doi: 10.1002/adhm.202203022. Epub 2023 Mar 21. Adv Healthc Mater. 2023. PMID: 36906918 Free PMC article.