Hay RT - Search Results

1

RNF12 X-Linked Intellectual Disability Mutations Disrupt E3 Ligase Activity and Neural Differentiation.

Bustos F, Segarra-Fas A, Chaugule VK, Brandenburg L, Branigan E, Toth R, Macartney T, Knebel A, Hay RT, Walden H, Findlay GM. Bustos F, et al. Among authors: hay rt. Cell Rep. 2018 May 8;23(6):1599-1611. doi: 10.1016/j.celrep.2018.04.022. Cell Rep. 2018. PMID: 29742418 Free PMC article.

2

Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity.

Xirodimas DP, Saville MK, Bourdon JC, Hay RT, Lane DP. Xirodimas DP, et al. Among authors: hay rt. Cell. 2004 Jul 9;118(1):83-97. doi: 10.1016/j.cell.2004.06.016. Cell. 2004. PMID: 15242646 Free article.

3

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation.

Tatham MH, Geoffroy MC, Shen L, Plechanovova A, Hattersley N, Jaffray EG, Palvimo JJ, Hay RT. Tatham MH, et al. Among authors: hay rt. Nat Cell Biol. 2008 May;10(5):538-46. doi: 10.1038/ncb1716. Epub 2008 Apr 13. Nat Cell Biol. 2008. PMID: 18408734

4

An additional role for SUMO in ubiquitin-mediated proteolysis.

Geoffroy MC, Hay RT. Geoffroy MC, et al. Among authors: hay rt. Nat Rev Mol Cell Biol. 2009 Aug;10(8):564-8. doi: 10.1038/nrm2707. Epub 2009 May 28. Nat Rev Mol Cell Biol. 2009. PMID: 19474794 Review.

5

Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis.

Plechanovová A, Jaffray EG, Tatham MH, Naismith JH, Hay RT. Plechanovová A, et al. Among authors: hay rt. Nature. 2012 Sep 6;489(7414):115-20. doi: 10.1038/nature11376. Nature. 2012. PMID: 22842904 Free PMC article.

6

PML isoforms in response to arsenic: high-resolution analysis of PML body structure and degradation.

Hands KJ, Cuchet-Lourenco D, Everett RD, Hay RT. Hands KJ, et al. Among authors: hay rt. J Cell Sci. 2014 Jan 15;127(Pt 2):365-75. doi: 10.1242/jcs.132290. Epub 2013 Nov 4. J Cell Sci. 2014. PMID: 24190887 Free PMC article.

7

SUMO chain-induced dimerization activates RNF4.

Rojas-Fernandez A, Plechanovová A, Hattersley N, Jaffray E, Tatham MH, Hay RT. Rojas-Fernandez A, et al. Among authors: hay rt. Mol Cell. 2014 Mar 20;53(6):880-92. doi: 10.1016/j.molcel.2014.02.031. Mol Cell. 2014. PMID: 24656128 Free PMC article.

8

Ubiquitin C-terminal hydrolases cleave isopeptide- and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers.

Bett JS, Ritorto MS, Ewan R, Jaffray EG, Virdee S, Chin JW, Knebel A, Kurz T, Trost M, Tatham MH, Hay RT. Bett JS, et al. Among authors: hay rt. Biochem J. 2015 Mar 15;466(3):489-98. doi: 10.1042/BJ20141349. Biochem J. 2015. PMID: 25489924 Free PMC article.

9

Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9.

Rojas-Fernandez A, Herhaus L, Macartney T, Lachaud C, Hay RT, Sapkota GP. Rojas-Fernandez A, et al. Among authors: hay rt. Sci Rep. 2015 Apr 29;5:9811. doi: 10.1038/srep09811. Sci Rep. 2015. PMID: 25922883 Free PMC article.

10

Structural basis for the RING-catalyzed synthesis of K63-linked ubiquitin chains.

Branigan E, Plechanovová A, Jaffray EG, Naismith JH, Hay RT. Branigan E, et al. Among authors: hay rt. Nat Struct Mol Biol. 2015 Aug;22(8):597-602. doi: 10.1038/nsmb.3052. Epub 2015 Jul 6. Nat Struct Mol Biol. 2015. PMID: 26148049 Free PMC article.

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