Hanson MA - Search Results

1

High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening.

Qin S, Meng M, Yang D, Bai W, Lu Y, Peng Y, Song G, Wu Y, Zhou Q, Zhao S, Huang X, McCorvy JD, Cai X, Dai A, Roth BL, Hanson MA, Liu ZJ, Wang MW, Stevens RC, Shui W. Qin S, et al. Among authors: hanson ma. Chem Sci. 2018 Feb 20;9(12):3192-3199. doi: 10.1039/c7sc04698g. eCollection 2018 Mar 28. Chem Sci. 2018. PMID: 29732102 Free PMC article.

2

Cocrystal structure of synaptobrevin-II bound to botulinum neurotoxin type B at 2.0 A resolution.

Hanson MA, Stevens RC. Hanson MA, et al. Nat Struct Biol. 2000 Aug;7(8):687-92. doi: 10.1038/77997. Nat Struct Biol. 2000. Retraction in: Nat Struct Mol Biol. 2009 Jul;16(7):795. doi: 10.1038/nsmb0709-795 PMID: 10932255 Retracted.

3

Structural adaptations in a membrane enzyme that terminates endocannabinoid signaling.

Bracey MH, Hanson MA, Masuda KR, Stevens RC, Cravatt BF. Bracey MH, et al. Among authors: hanson ma. Science. 2002 Nov 29;298(5599):1793-6. doi: 10.1126/science.1076535. Science. 2002. PMID: 12459591

4

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function.

Rosenbaum DM, Cherezov V, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Yao XJ, Weis WI, Stevens RC, Kobilka BK. Rosenbaum DM, et al. Among authors: hanson ma. Science. 2007 Nov 23;318(5854):1266-73. doi: 10.1126/science.1150609. Epub 2007 Oct 25. Science. 2007. PMID: 17962519

5

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor.

Cherezov V, Rosenbaum DM, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Kuhn P, Weis WI, Kobilka BK, Stevens RC. Cherezov V, et al. Among authors: hanson ma. Science. 2007 Nov 23;318(5854):1258-65. doi: 10.1126/science.1150577. Epub 2007 Oct 25. Science. 2007. PMID: 17962520 Free PMC article.

6

Stabilization of the human beta2-adrenergic receptor TM4-TM3-TM5 helix interface by mutagenesis of Glu122(3.41), a critical residue in GPCR structure.

Roth CB, Hanson MA, Stevens RC. Roth CB, et al. Among authors: hanson ma. J Mol Biol. 2008 Mar 7;376(5):1305-19. doi: 10.1016/j.jmb.2007.12.028. Epub 2007 Dec 23. J Mol Biol. 2008. PMID: 18222471 Free PMC article.

7

A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor.

Hanson MA, Cherezov V, Griffith MT, Roth CB, Jaakola VP, Chien EY, Velasquez J, Kuhn P, Stevens RC. Hanson MA, et al. Structure. 2008 Jun;16(6):897-905. doi: 10.1016/j.str.2008.05.001. Structure. 2008. PMID: 18547522 Free PMC article.

8

The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist.

Jaakola VP, Griffith MT, Hanson MA, Cherezov V, Chien EY, Lane JR, Ijzerman AP, Stevens RC. Jaakola VP, et al. Among authors: hanson ma. Science. 2008 Nov 21;322(5905):1211-7. doi: 10.1126/science.1164772. Epub 2008 Oct 2. Science. 2008. PMID: 18832607 Free PMC article.

9

Discovery of new GPCR biology: one receptor structure at a time.

Hanson MA, Stevens RC. Hanson MA, et al. Structure. 2009 Jan 14;17(1):8-14. doi: 10.1016/j.str.2008.12.003. Structure. 2009. PMID: 19141277 Free PMC article. Review.

10

LCP-FRAP Assay for Pre-Screening Membrane Proteins for in Meso Crystallization.

Cherezov V, Liu J, Griffith M, Hanson MA, Stevens RC. Cherezov V, et al. Among authors: hanson ma. Cryst Growth Des. 2008;8(12):4307-4315. doi: 10.1021/cg800778j. Cryst Growth Des. 2008. PMID: 19234616 Free PMC article.

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