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Early-onset pediatric atopic dermatitis is characterized by TH2/TH17/TH22-centered inflammation and lipid alterations.
Brunner PM, Israel A, Zhang N, Leonard A, Wen HC, Huynh T, Tran G, Lyon S, Rodriguez G, Immaneni S, Wagner A, Zheng X, Estrada YD, Xu H, Krueger JG, Paller AS, Guttman-Yassky E. Brunner PM, et al. Among authors: krueger jg. J Allergy Clin Immunol. 2018 Jun;141(6):2094-2106. doi: 10.1016/j.jaci.2018.02.040. Epub 2018 May 3. J Allergy Clin Immunol. 2018. PMID: 29731129
Human basal cell carcinoma is associated with Foxp3+ T cells in a Th2 dominant microenvironment.
Kaporis HG, Guttman-Yassky E, Lowes MA, Haider AS, Fuentes-Duculan J, Darabi K, Whynot-Ertelt J, Khatcherian A, Cardinale I, Novitskaya I, Krueger JG, Carucci JA. Kaporis HG, et al. Among authors: krueger jg. J Invest Dermatol. 2007 Oct;127(10):2391-8. doi: 10.1038/sj.jid.5700884. Epub 2007 May 17. J Invest Dermatol. 2007. PMID: 17508019 Free article.
Blockade of CD11a by efalizumab in psoriasis patients induces a unique state of T-cell hyporesponsiveness.
Guttman-Yassky E, Vugmeyster Y, Lowes MA, Chamian F, Kikuchi T, Kagen M, Gilleaudeau P, Lee E, Hunte B, Howell K, Dummer W, Bodary SC, Krueger JG. Guttman-Yassky E, et al. Among authors: krueger jg. J Invest Dermatol. 2008 May;128(5):1182-91. doi: 10.1038/jid.2008.4. Epub 2008 Jan 31. J Invest Dermatol. 2008. PMID: 18239614 Free article. Clinical Trial.
Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways.
Nograles KE, Zaba LC, Guttman-Yassky E, Fuentes-Duculan J, Suárez-Fariñas M, Cardinale I, Khatcherian A, Gonzalez J, Pierson KC, White TR, Pensabene C, Coats I, Novitskaya I, Lowes MA, Krueger JG. Nograles KE, et al. Among authors: krueger jg. Br J Dermatol. 2008 Nov;159(5):1092-102. doi: 10.1111/j.1365-2133.2008.08769.x. Epub 2008 Aug 5. Br J Dermatol. 2008. PMID: 18684158 Free PMC article.
Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis.
Guttman-Yassky E, Lowes MA, Fuentes-Duculan J, Zaba LC, Cardinale I, Nograles KE, Khatcherian A, Novitskaya I, Carucci JA, Bergman R, Krueger JG. Guttman-Yassky E, et al. Among authors: krueger jg. J Immunol. 2008 Nov 15;181(10):7420-7. doi: 10.4049/jimmunol.181.10.7420. J Immunol. 2008. PMID: 18981165 Free PMC article.
IL-22-producing "T22" T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17-producing TH17 T cells.
Nograles KE, Zaba LC, Shemer A, Fuentes-Duculan J, Cardinale I, Kikuchi T, Ramon M, Bergman R, Krueger JG, Guttman-Yassky E. Nograles KE, et al. Among authors: krueger jg. J Allergy Clin Immunol. 2009 Jun;123(6):1244-52.e2. doi: 10.1016/j.jaci.2009.03.041. Epub 2009 May 12. J Allergy Clin Immunol. 2009. PMID: 19439349 Free PMC article.
466 results