Janssen HM - Search Results

1

Chemically triggered drug release from an antibody-drug conjugate leads to potent antitumour activity in mice.

Rossin R, Versteegen RM, Wu J, Khasanov A, Wessels HJ, Steenbergen EJ, Ten Hoeve W, Janssen HM, van Onzen AHAM, Hudson PJ, Robillard MS. Rossin R, et al. Among authors: janssen hm. Nat Commun. 2018 May 4;9(1):1484. doi: 10.1038/s41467-018-03880-y. Nat Commun. 2018. PMID: 29728559 Free PMC article.

2

Evaluation of strained alkynes for Cu-free click reaction in live mice.

van den Bosch SM, Rossin R, Renart Verkerk P, Ten Hoeve W, Janssen HM, Lub J, Robillard MS. van den Bosch SM, et al. Among authors: janssen hm. Nucl Med Biol. 2013 Apr;40(3):415-23. doi: 10.1016/j.nucmedbio.2012.12.006. Epub 2013 Feb 4. Nucl Med Biol. 2013. PMID: 23380519

3

Click to release: instantaneous doxorubicin elimination upon tetrazine ligation.

Versteegen RM, Rossin R, ten Hoeve W, Janssen HM, Robillard MS. Versteegen RM, et al. Among authors: janssen hm. Angew Chem Int Ed Engl. 2013 Dec 23;52(52):14112-6. doi: 10.1002/anie.201305969. Epub 2013 Nov 26. Angew Chem Int Ed Engl. 2013. PMID: 24281986 No abstract available.

4

Triggered Drug Release from an Antibody-Drug Conjugate Using Fast "Click-to-Release" Chemistry in Mice.

Rossin R, van Duijnhoven SM, Ten Hoeve W, Janssen HM, Kleijn LH, Hoeben FJ, Versteegen RM, Robillard MS. Rossin R, et al. Among authors: janssen hm. Bioconjug Chem. 2016 Jul 20;27(7):1697-706. doi: 10.1021/acs.bioconjchem.6b00231. Epub 2016 Jun 29. Bioconjug Chem. 2016. PMID: 27306828

5

Efficient Functionalization of Additives at Supramolecular Material Surfaces.

Goor OJ, Keizer HM, Bruinen AL, Schmitz MG, Versteegen RM, Janssen HM, Heeren RM, Dankers PY. Goor OJ, et al. Among authors: janssen hm. Adv Mater. 2017 Feb;29(5). doi: 10.1002/adma.201604652. Epub 2016 Nov 29. Adv Mater. 2017. PMID: 27896852

6

DOTA-tetrazine probes with modified linkers for tumor pretargeting.

Läppchen T, Rossin R, van Mourik TR, Gruntz G, Hoeben FJM, Versteegen RM, Janssen HM, Lub J, Robillard MS. Läppchen T, et al. Among authors: janssen hm. Nucl Med Biol. 2017 Dec;55:19-26. doi: 10.1016/j.nucmedbio.2017.09.001. Epub 2017 Sep 14. Nucl Med Biol. 2017. PMID: 29028502

7

Click-to-Release from trans-Cyclooctenes: Mechanistic Insights and Expansion of Scope from Established Carbamate to Remarkable Ether Cleavage.

Versteegen RM, Ten Hoeve W, Rossin R, de Geus MAR, Janssen HM, Robillard MS. Versteegen RM, et al. Among authors: janssen hm. Angew Chem Int Ed Engl. 2018 Aug 13;57(33):10494-10499. doi: 10.1002/anie.201800402. Epub 2018 Jun 27. Angew Chem Int Ed Engl. 2018. PMID: 29746709

8

Author Correction: Chemically triggered drug release from an antibody-drug conjugate leads to potent antitumour activity in mice.

Rossin R, Versteegen RM, Wu J, Khasanov A, Wessels HJ, Steenbergen EJ, Ten Hoeve W, Janssen HM, van Onzen AHAM, Hudson PJ, Robillard MS. Rossin R, et al. Among authors: janssen hm. Nat Commun. 2019 Jan 16;10(1):363. doi: 10.1038/s41467-019-08376-x. Nat Commun. 2019. PMID: 30651544 Free PMC article.

9

Bioorthogonal Tetrazine Carbamate Cleavage by Highly Reactive trans-Cyclooctene.

van Onzen AHAM, Versteegen RM, Hoeben FJM, Filot IAW, Rossin R, Zhu T, Wu J, Hudson PJ, Janssen HM, Ten Hoeve W, Robillard MS. van Onzen AHAM, et al. Among authors: janssen hm. J Am Chem Soc. 2020 Jun 24;142(25):10955-10963. doi: 10.1021/jacs.0c00531. Epub 2020 Jun 10. J Am Chem Soc. 2020. PMID: 32453557

10

Ortho-functionalized pyridinyl-tetrazines break the inverse correlation between click reactivity and cleavage yields in click-to-release chemistry.

Versteegen RM, Rossin R, Filot IAW, Hoeben FJM, van Onzen AHAM, Janssen HM, Robillard MS. Versteegen RM, et al. Among authors: janssen hm. Commun Chem. 2024 Dec 19;7(1):302. doi: 10.1038/s42004-024-01392-z. Commun Chem. 2024. PMID: 39702778 Free PMC article.

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