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Repression of GSK3 restores NK cell cytotoxicity in AML patients.
Parameswaran R, Ramakrishnan P, Moreton SA, Xia Z, Hou Y, Lee DA, Gupta K, deLima M, Beck RC, Wald DN. Parameswaran R, et al. Among authors: wald dn. Nat Commun. 2016 Apr 4;7:11154. doi: 10.1038/ncomms11154. Nat Commun. 2016. PMID: 27040177 Free PMC article.
Aberrant GSK3β nuclear localization promotes AML growth and drug resistance.
Ignatz-Hoover JJ, Wang V, Mackowski NM, Roe AJ, Ghansah IK, Ueda M, Lazarus HM, de Lima M, Paietta E, Fernandez H, Cripe L, Tallman M, Wald DN. Ignatz-Hoover JJ, et al. Among authors: wald dn. Blood Adv. 2018 Nov 13;2(21):2890-2903. doi: 10.1182/bloodadvances.2018016006. Blood Adv. 2018. PMID: 30385433 Free PMC article.
Low-Dose Azacitidine with DNMT1 Level Monitoring to Treat Post-Transplantation Acute Myelogenous Leukemia or Myelodysplastic Syndrome Relapse.
Ueda M, El-Jurdi N, Cooper B, Caimi P, Baer L, Kolk M, Brister L, Wald DN, Otegbeye F, Lazarus HM, Sandmaier BM, William B, Saunthararajah Y, Woost P, Jacobberger JW, de Lima M. Ueda M, et al. Among authors: wald dn. Biol Blood Marrow Transplant. 2019 Jun;25(6):1122-1127. doi: 10.1016/j.bbmt.2018.12.764. Epub 2018 Dec 30. Biol Blood Marrow Transplant. 2019. PMID: 30599207 Free article.
Thioredoxin reductase is a major regulator of metabolism in leukemia cells.
Karunanithi S, Liu R, Hou Y, Gonzalez G, Oldford N, Roe AJ, Idipilly N, Gupta K, Amara CS, Putluri S, Lee GK, Valentin-Goyco J, Stetson L, Moreton SA, Putluri V, Kavuri SM, Saunthararajah Y, de Lima M, Tochtrop GP, Putluri N, Wald DN. Karunanithi S, et al. Among authors: wald dn. Oncogene. 2021 Aug;40(33):5236-5246. doi: 10.1038/s41388-021-01924-0. Epub 2021 Jul 8. Oncogene. 2021. PMID: 34239044 Free PMC article.
A Phase I Study to Determine the Maximum Tolerated Dose of ex Vivo Expanded Natural Killer Cells Derived from Unrelated, HLA-Disparate Adult Donors.
Otegbeye F, Cooper B, Caimi P, Zamborsky K, Reese-Koc J, Hillian A, Hernandez-Collazo Y, Lee G, Boughan K, Tomlinson B, Gallogly M, Metheny L, Bajor D, Selfridge J, Saltzman J, Lazarus H, de Lima M, Wald D. Otegbeye F, et al. Transplant Cell Ther. 2022 May;28(5):250.e1-250.e8. doi: 10.1016/j.jtct.2022.02.008. Epub 2022 Feb 14. Transplant Cell Ther. 2022. PMID: 35172204 Free PMC article. Clinical Trial.
Flow cytometry of DNMT1 as a biomarker of hypomethylating therapies.
Woost PG, William BM, Cooper BW, Ueda Oshima M, Otegbeye F, De Lima MJ, Wald D, Mahfouz RZ, Saunthararajah Y, Stefan T, Jacobberger JW. Woost PG, et al. Cytometry B Clin Cytom. 2024 Jan;106(1):11-24. doi: 10.1002/cyto.b.22158. Epub 2024 Feb 12. Cytometry B Clin Cytom. 2024. PMID: 38345160 Free article.
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